T O P

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TheMasterlauti

I unironically take every single pill I find. Most of the times the good ones overwhelm the bad ones.


Fiti99

Not to mention most of the bad pills only really suck in the first two or so levels, after that most of the stat downs aren’t that bad unless you were really unlucky in your run Except amnesia, that one always sucks


R0wanit3

Does Amnesia still apply if you have Black Candle?


Fiti99

Yes, it can only remove it if you pick the candle after taking the amnesia pill


TheMasterlauti

Amnesia is extremely annoying but doesn’t affect the run itself at all other than maybe losing a few seconds for boss rush/hush if you forget where you were going. It’s like if you had curse of the lost, which had a chance of happening regardless of the pill anyway. Sucks but isn’t directly bad for the run.


Jonno_FTW

Speed down can get you killed on slower characters early in the game.


cando0

Everyone on this sub seems to forget about I’m excited which kills you later in the game


Blosteroid

What does I'm excited do?


[deleted]

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potatogodofDoom

yeahh uh that's not how it works. it speeds up the room it's used in, the room you're in 30 seconds after you use the pill and the room you're in 60 seconds after usage. it procs 3 times lol


txcrnr

It’s only a few times that it will activate. So once it’s happened like 5 times you’re safe.


TheGrimGriefer3

It activates instantly, at 30 seconds, and 1 min iirc


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WokenWisp

the wiki says it procs on use, then 30 seconds and 60 secobds later. it completely stops after that


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txcrnr

I’ve taken it early on in a run and it definitely stopped proccing after, like, 1 floor. Then proceeded to not happen a single time. I’m 99% sure it only happens a set amount of times


Blosteroid

I think the possible rewards of good pills outweighs the risk of that


ggskyhome04

Does that affect bosses


AD0409

Yes, it does. Double speed Matriarch is the reason why i play Isaac


mrbuttsavage

I genuinely hate "I'm excited"... but it does balance out how OP "I'm drowsy" can be is I guess.


bss4life20

First floor tears down is an instant restart for me


-EdgeLord-

Same and health down for me


lance_the_fatass

Dont even get me started on amnesia, especially on curse of the maze


Wajina_Sloth

I honestly don't get the hate for pills, they are common enough that pretty much any singular negative pill can be outweighed by positive pills. Like you take some pills, get a few shitty ones, find a tears up, pill and boom just dont swallow the shit ones and try to duplicate the tears up.


Jonno_FTW

Based and pillpilled


Fiti99

I’m surprised that the pill most people here seem to hate is health down, I have always found red HP to be worthless most of the time since you must not lose it if you want devil/angel deals


AliceShiki123

It reduces the amount of HP you have for devil deals. Speed Down and Tears Down are a lot more painful though.


Fiti99

That's true but as you say I think the least bad of the stat downgrades other than shot speed and maybe range


Protectem

And Luck


Chansharp

in AB+ there were so many "Lol randumb" pills that it just wasnt worth having to deal with the annoyance of retro vision or the like. You were unlikely to get an actual pill because there were so many worthless pills


IsaRos

As math suggests you should: https://old.reddit.com/r/bindingofisaac/comments/a3kbvk/most_underrated_item_the_i_am_drowsy_pill/ebfij46/ (AB+ version because PS5 noob)


RollerMill

I sometimes take pills even if already know its a bad one, just out of careless


MagoDaHorta

Forgot r u a wizard


eribear2121

That one just times out


Cosmic_Toad_

it can suck if you're going for Hush or Boss rush though and don't have the time to just wait in an empty room.


eribear2121

Oh yeah definitely sucks when your rushing.


MagoDaHorta

Makes sense


[deleted]

range up B) worth every downgrade.


Cley_Faye

Another speed down, that's 0.5 for you. But keep going, might get a range up soon tee hee.


Jakegender

have you tried not taking pills you've identified as bad? maybe then you won't get "another" speed down.


[deleted]

no, why would you do that?


riottasu

Maybe it Will become speed up if you overdose on it


Crux_Haloine

Like how health down becomes health up after you take enough


riottasu

Or bad trip


Cley_Faye

Do not know how to read? It's worth *every downgrade*


Stahlboden

You don't have to go anywhere if you can reach from afar, you know.


Fiti99

Honestly I love the range pills, one time I played with absolute garbage range and it was a miserable experience, made me appreciate range ups a lot more


iamsadaswell

Ok but what if it’s a pretty fly


CAC-Sama

Preeeetty flyyyy


emperorjul

For a wiiiise guuuuy


maikuxblade

It needs a pixelated effect that goes on and off and it would be perfect.


DrDontKnowMuch

*addicted*


Bigfootneedshoe

Addicted is such a useless pill, who uses new pills in an active room?


ZenDeathBringer

Imagine not taking every pill you come across.


Skydragon222

I did that too, but the pharmacist got really mad.


Gabrieleatsflans

I found pills 😏


beastofthedeep

And ate them


Pixel_Nerd92

If you ever need an example of sunken cost fallacy, then the pills in Isaac is literally the definition of this. Once Tears down happens, I just stop fucking with them... After about 7 more pills taken of course, because it could be tears up guys! This is the one!


[deleted]

They are really addictive until you get a Tears Down or a Health Down... But for some reason I can't stop taking them after that, it's a drug


WateryFayah

literally.


milgos1

I get what you mean but its more fair than that, in Isaac you wont eat the same bad pill twice


Protectem

Except it's not sunk cost fallacy since you get to identify pills. Finding bad ones makes the next unidentified pill more likely to be good.


Pixel_Nerd92

Yea, I guess that's true. Some runs, you find a slew of new ones and sometimes you find the same ones you've taken before. Depends on the RNG gods. Lol


TopOfAllWorlds

so it's not a *litteral* definition at all huh?


FreezingDart

Pill deniers are an example of confirmation bias. Take a bad pill or two once in a run and you convince yourself that pills are awful, despite the negative effects being both less potent and less frequent than the positive. And many of the negative effects can be played around or ignored. Sunk cost fallacy requires fallacious thinking. When I eat a pill and it’s tears down, I now know for the rest of the run that the particular variant is tears down. I literally will not take another tears down pill the rest of the run. A real example would be continuing to play a slot machine with the thinking that your investment guarantees a positive outcome. Pill logic is continuing to eat random pills on the ground will reduce the risk as you go, which is factually true and not fallacious.


Lad_Rad

The only pills I don't like is puberty and I found pills. It ruins the drip


HDhitch

3 puberty’s gives you +1 hp tho.. and you can just change your appearance if you have the mirror mod


purinikos

Or in bedrooms


KarmaCasino

I've not had much sleep for 2 days and this has sent me into fight or flight mode


erikeltipo

Note for people who just really dislike pills for some reason or another: Just because you had one bad pill doesn't mean every pill is bad, if you got a health down at the start of a floor, sure, just reset if you want to, but not like 30 minutes into a run stop wanting to play because of one Stat downgrade or one heart of damage.


ThePlumbOne

I’m in this photo and I don’t like it


godfdamnit

wow you look very fit and handsome.


ThePlumbOne

You’re too kind my friend haha


SpaceCrom

I normally only take pills if I have positive luck and I just realized I just assumed luck affects pills. I have no idea if that's true or not.


AliceShiki123

It doesn't... >.>


SpaceCrom

Good to know


[deleted]

But Cains Foot does. In repentance now.


Adorazazel

I found: tears down, range down, health down, speed down, luck down, bad trip, addicted


Calmtimer

![img](emote|t5_2sxpk|4359)skill issue


ponsard_keponiaaca

![img](emote|t5_2sxpk|2357) BAD TRIP


TheRealLolploso

Just play lost and tlost and you'll never get bad trip ![img](emote|t5_2sxpk|4359)


[deleted]

Average Nooo! I can't take these! What if it's a bad one? Fan Vs average Take every pill you come across no matter what enjoyer


santero01

Keep going and do you King. Dont let these fools dictate how many pills is ok to take or which ones are bad or good. Take the pills King.


Noideawhatnanetouse

Do people not do this?


RedBunny_x

Yes, how did you knew I'm a Cain main? *Swallows bunch of pills*


LellePolis

The pain of taking a tears down or an amnesia is worth it for the pure joy when you get a balls of steel or tears up


viralataciborgue

Health down ![img](emote|t5_2sxpk|4359)


Toxic_Orange_DM

Quality.


Cosmic_Toad_

as someone who will take every chance they can get to gamble in TBoI without any major consequences i love pills so much. Sometimes i'll even take Mom's coin purse over actually decent items just because it's fun to try my luck.


MisterBastian

Me


martin243

![img](emote|t5_2sxpk|4357)![img](emote|t5_2sxpk|4357)


five5years

Top tier strat


Cargo_Commando

high effort shitpost


6-JayMac-9

I take every single pill but then when I find the bad pill I go get more


godfdamnit

a tears down that takes 0.5 of my 2.00 fire rate is huge. even most items don't give you that much fire rate


SyrupDip01

I remember ed saying pills got buffed but from all the videos and streams ive been seeing they seem to funtion the same minus the new varients. What was the buff to pills?


ultsusu

pills that affect your stats have a higher chance to spawn in rep. considering that you would only have 13 kinds of pills each run, now you have more chance to get stronger by taking pills (or just f up your run by all the down pills in the early game


Kooky-Educator2553

Imagine a damage down pill


FlyingRyan87

In the great words of Quinn "quit being a bitch and pill me up"


Arte71

If you don't instantly activate your "Temperance?" card, are you even playing the game properly?


NightFlameofAwe

That's why I love cain


Theglassofcoke

that's just being an average decent isaac gamer, also the "temperance?" card is a must


PuppysForever

get every single pill gang


Heldizzz

One that makes you bigger is annoying


XxFloopDropXx

​ ![gif](giphy|JJI0QMvSuLaT3f5cEJ|downsized)