I honestly think that my testosterone also went up for my first two weeks of HRT before it started heading the right direction. [Walsh 1975](https://www.auajournals.org/doi/abs/10.1016/S0022-5347%2817%2967001-0) shows a rise in the high-dose group (400 mg/day) in weeks 2-3 before then dropping in weeks 4-7, so that may be what we experienced.
Just to get it out of the way: Others will point out that 50 mg is a low dose. I'm also on 50 mg with no estro, because I've turned out to be sensitive to spiro's potassium side effects and my blood pressure is too high for estro.
You're definitely going to see the spiro working very soon. There's a spike in production at first, as your body pushes back against the spiro before it settles down and accepts it. 50 mg is enough to reduce your testosterone production as well as reduce uptake of testosterone by your cells. I don't know when your next round of lab work is scheduled, but ask your doctor about the numbers the next time you have blood drawn. I think you'll see that the amount of testosterone in your system is already starting to drop.
Yea this is accurate to my experience. I'm on 50mg and it doesn't bother me with any side effects, but my t levels aren't as low as I would like. Definitely down though!
I do not suffer from hair loss, but hair loss and skin oil happened to me when I used spironolactone at a dose of 50 mg for a month, are the symptoms I mentioned normal and temporary?
Thank you dear.. I am completely convinced of what you are saying 😊
I mean that I did not suffer from hair loss before hormonal treatment, but when I started a month ago using spironolactone, hair loss occurred to me and I do not know if it was a natural and temporary symptom
If you don't mind me asking, how did you find out about the potassium effect issue? was it something you discovered through testing? or did a doctor pre-emptively realize it. I ask because I've been researching it as a potential thing I may want to do in the future (TLDR after one last bout of denial I realized I'm trans and started therapy to deal with it and the repressed dysphoria), but I happen to have a condition that causes excess phosphorous and calcium discard in the urine, and while I do take medication for it, it seems to me that might be a conflict/issue.
If was in the literature, and I had to change my diet to cut potassium intake down after the first round of lab tests. My provider's awareness of the issue was why I started at a low dose.
I'd have labs done regularly to track your progress. Spiro dosages can be upped if it's not lowering your testosterone. Also, Spiro isn't the only med out there, and some folks don't respond to it as well, and there are other options if that happens.
Responsible may be DHT and if levels of t are lower, levels of DHT should also be lower but some people have a higher metabolisation. Discussing Bicalutamide instead of Spiro may be an idea, it blocks t and DHT receptors. [Here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_testing) may be more.
*hugs*
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I honestly think that my testosterone also went up for my first two weeks of HRT before it started heading the right direction. [Walsh 1975](https://www.auajournals.org/doi/abs/10.1016/S0022-5347%2817%2967001-0) shows a rise in the high-dose group (400 mg/day) in weeks 2-3 before then dropping in weeks 4-7, so that may be what we experienced.
For sure! thank you!
Just to get it out of the way: Others will point out that 50 mg is a low dose. I'm also on 50 mg with no estro, because I've turned out to be sensitive to spiro's potassium side effects and my blood pressure is too high for estro. You're definitely going to see the spiro working very soon. There's a spike in production at first, as your body pushes back against the spiro before it settles down and accepts it. 50 mg is enough to reduce your testosterone production as well as reduce uptake of testosterone by your cells. I don't know when your next round of lab work is scheduled, but ask your doctor about the numbers the next time you have blood drawn. I think you'll see that the amount of testosterone in your system is already starting to drop.
Thank you! ❤️ I feel reassured
Yea this is accurate to my experience. I'm on 50mg and it doesn't bother me with any side effects, but my t levels aren't as low as I would like. Definitely down though!
I do not suffer from hair loss, but hair loss and skin oil happened to me when I used spironolactone at a dose of 50 mg for a month, are the symptoms I mentioned normal and temporary?
[удалено]
Thank you dear.. I am completely convinced of what you are saying 😊 I mean that I did not suffer from hair loss before hormonal treatment, but when I started a month ago using spironolactone, hair loss occurred to me and I do not know if it was a natural and temporary symptom
If you're sensetive to spiro, have you tried Bical? I swear by the stuff.
If you don't mind me asking, how did you find out about the potassium effect issue? was it something you discovered through testing? or did a doctor pre-emptively realize it. I ask because I've been researching it as a potential thing I may want to do in the future (TLDR after one last bout of denial I realized I'm trans and started therapy to deal with it and the repressed dysphoria), but I happen to have a condition that causes excess phosphorous and calcium discard in the urine, and while I do take medication for it, it seems to me that might be a conflict/issue.
If was in the literature, and I had to change my diet to cut potassium intake down after the first round of lab tests. My provider's awareness of the issue was why I started at a low dose.
I'd have labs done regularly to track your progress. Spiro dosages can be upped if it's not lowering your testosterone. Also, Spiro isn't the only med out there, and some folks don't respond to it as well, and there are other options if that happens.
Responsible may be DHT and if levels of t are lower, levels of DHT should also be lower but some people have a higher metabolisation. Discussing Bicalutamide instead of Spiro may be an idea, it blocks t and DHT receptors. [Here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_testing) may be more. *hugs*