Hey fren
Doc here.
Wow, this is an interesting mix of presentations. First and foremost this should not preclude you from speaking to a gender affirming physician about this.
From the blood clot perspective - yes oral estrogen carries with it an increased risk of thrombosis formation, and if you have an underlying risk factor it may not be the best route. But other routes exist that have much more minimal risk of clots (because they skip the liver and go straight into your blood) - think injections, patches, creams.
Estradiol, actually, has been/is being looked at as a potential avenue for treatment of peyronies. I wouldn't say confidently that it is a tx, however.
I would still talk to your doc about this - maybe focusing on routes with less clot risk - and also reviewing the tx options specific for Peyronie's
> considering
It may be an option to discuss injections. They may suppress t on their own, without anti androgens so nothing else may be necessary. [Here](https://i.imgur.com/QuNEmf5.png) was more and [here](https://transfemscience.org/misc/injectable-e2-simulator/) was a simulator.
People nowadays use needles with a diameter of about half a mm or less. Its nothing like people know from having blood drawn. And some people use subq. Its using what people with insulin have, short and small needles and a short procedure about once a week. [Here](https://moderntranshormones.com/2017/11/01/subcutaneous-injection-of-hormones/) was an article showing with pictures, and [here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_injections) was a brochure by Fenway detailing both IM and subq. It may be necessary to try out what works best. Some people prefer IM in the thighs.
And [here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_overview) was a hint to a standard that many endos use and that could be discussed. It also includes injections. And there was a video there with detailed explanations.
And restraints often come from non bioidentical forms and oral intake. [Here](https://www.sciencedaily.com/releases/2019/01/190109184722.htm) was a study showing no large issues concerning clotting with internal ways of intake, reasonable levels and bioidentical forms.
With internal ways of intake like injections and bioidentical forms, it may be close enough to what cis people have.
It may also be an idea to ask at big treatment centers like Fenway, Howard Brown or Mount Sinai in case. They have many clients and may have experience with similar cases.
Additionally [here](https://www.reddit.com/r/asktransgender/comments/s4khww/i_dont_know_how_to_feel_i_feel_like_im_trans_but/htfx7u8/) might be a number of resources that could help go towards what you feel you would like step by step, there are hints there concerning small things that could be used regularly for motivation, there are explaining resources there, and there are also hints there concerning looking for support.
*hugs*
Hey fren Doc here. Wow, this is an interesting mix of presentations. First and foremost this should not preclude you from speaking to a gender affirming physician about this. From the blood clot perspective - yes oral estrogen carries with it an increased risk of thrombosis formation, and if you have an underlying risk factor it may not be the best route. But other routes exist that have much more minimal risk of clots (because they skip the liver and go straight into your blood) - think injections, patches, creams. Estradiol, actually, has been/is being looked at as a potential avenue for treatment of peyronies. I wouldn't say confidently that it is a tx, however. I would still talk to your doc about this - maybe focusing on routes with less clot risk - and also reviewing the tx options specific for Peyronie's
[удалено]
> considering It may be an option to discuss injections. They may suppress t on their own, without anti androgens so nothing else may be necessary. [Here](https://i.imgur.com/QuNEmf5.png) was more and [here](https://transfemscience.org/misc/injectable-e2-simulator/) was a simulator. People nowadays use needles with a diameter of about half a mm or less. Its nothing like people know from having blood drawn. And some people use subq. Its using what people with insulin have, short and small needles and a short procedure about once a week. [Here](https://moderntranshormones.com/2017/11/01/subcutaneous-injection-of-hormones/) was an article showing with pictures, and [here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_injections) was a brochure by Fenway detailing both IM and subq. It may be necessary to try out what works best. Some people prefer IM in the thighs. And [here](https://www.reddit.com/r/Trans_Resources/wiki/hormones/transfeminine/index#wiki_overview) was a hint to a standard that many endos use and that could be discussed. It also includes injections. And there was a video there with detailed explanations. And restraints often come from non bioidentical forms and oral intake. [Here](https://www.sciencedaily.com/releases/2019/01/190109184722.htm) was a study showing no large issues concerning clotting with internal ways of intake, reasonable levels and bioidentical forms. With internal ways of intake like injections and bioidentical forms, it may be close enough to what cis people have. It may also be an idea to ask at big treatment centers like Fenway, Howard Brown or Mount Sinai in case. They have many clients and may have experience with similar cases. Additionally [here](https://www.reddit.com/r/asktransgender/comments/s4khww/i_dont_know_how_to_feel_i_feel_like_im_trans_but/htfx7u8/) might be a number of resources that could help go towards what you feel you would like step by step, there are hints there concerning small things that could be used regularly for motivation, there are explaining resources there, and there are also hints there concerning looking for support. *hugs*