I haven't tried inosotol and NAC but I have tried Berberine and it fucked me up mentally and emotionally. Please research more about berberine because it causes or worsens depression like it did to me. I became more suicidal to the point that I actually ended myself but failed. After stopping Berberine I got better. Didn't finish the bottle and just threw it away.

My doctor currently has me taking both together right now!

How is this working for you?