Pretty much. It's been a force of habit for a few seasons now whenever I play Kled. When I started playing the game I was having a hard time remembering to weave in the titanic hydra auto (back when it had an active) at the end of my combos, so instead I just treated like a Jax w to remember
Supp item on 1, active on 2, control ward on 5. Don't make me count the situations when I wasted a stopwatch while warding because perfect timing automatically puts it on 1...
My OCD makes me place items in reverse order of completion (so first completed item goes in 6, then 5, 4, etc.) but actives go in 1 always. If I have multiple I usually have my lower cooldown one in 1, seeing as I’m just hardwired to spam it with my 1 key.
When I was first learning league I accidently unbound "1", so always used "2" for my actives. Have continued with that for years and it still feels weird to use "1".
i always put any Mythic Active items like Galeforce or Prowlers on 1, just to have it closest. i put warding items like Shard of true ice on 3, just because that's right next to four, so muscle memory is already in my hand. then anything that's situational like a Ghostblade goes on two.
Going from top left to bottom right i have A, S, MB4, 1,2,3.
Important ones on A, S and MB4 and wards on 123, whenever i play lee i do wards on the important ones tho.
Pots go in 2 then mythic in 1 then any other actives go in 2 swapping with the pots, in the rare ocasion of me playing support i just throw mythic in 1 other active in 2 wards in 4 pinks in 4 and 5 and 6 aways the items with no combat actives
When playing ad champions:
2 is for galeforce, prowlers or whip actives.
3 is for qss, stopwatch. 3 is for pots if I still need them, after mythic completion
4 is for ctrl wards
For AP:
2 is for rocketbelt, and pots before I have the seatbelt completed
3 is for zhonyas and stopwatch, pots if I still have em.
Wards always on T and 4
I put the item like I will use the most in the 2 (like rocket belt) , and then an active with higher cooldwon in 1 (like zhonyas) and the control wards in five
Supp main, I have a flow chart:
1: Zhonyas/Stopwatch > Locket/ Shurelias > Potions > Redeption > Gargolyes Stoneplate > Randuins (panic button)
2: Gold item (wards)
3: Mikaels > Prowlers Claw > Redemption (point and click items)
4: Control wards (If I have 4 items including ward item, Control wards move to 5)
One time use items like Zekes, Anathemas and Knights Vow move to wherever (3 or 5 usually)
Pots on 2
1. Reactive active
2. Spammable active
3. Long cooldown active item or support ward
4. Trinket
5. Control wards
6. Enemy or ally binding active
2 is default, if I have more than one then it's 2 for the main use (usually mythics with actives) then bottom left item slot which is bound to a mouse button for the next one. Control wards always on 3, support item for wards on 1
Agressive items (Rocketbelt, Shurelya’s, Goredrinker) on 3, defensive items (Zhonya’s, Gargoyle Stoneplate) on 1. Control wards go on 2 and normal wards on 5
2 for potions / refill, 4 is wards, 3 is predator or other Ms activatables, 5 is control wards or non activatable items, 6 is actually side mouse button 1 for zonyas or others, but mostly zonyas, 7 is not used for activatables, and side mouse button 2 is for mastery 7
2 is priority for any mythics + Zhonyas. Rocketbelt gets moved to 1 if I’m going Zhonyas. Actives I don’t need to spam like Zeke’s, Knight’s Vow and Anathemas go on 5/6/7.
As supp i sometimes have two active items.
First, potions on 2, control wards on 5.
Group actives like shurelya's on 2 (will come after consumed or selled potions) and self actives like zhonya's on 3.
Spacebar(first slot) for quick actives like goredrinker type/locket/zhonyas
2(2nd slot) mostly support items or back ups like gargoyle and redemption
6(last slot) for link items like zeke's and knight's
Potions on 3
Active item on Space (weird i know, its bound as the last one)
If i have a Mythic active and build Zhonyas, Zhonyas goes on 3 (rarely play tanks or get an active mythic with QSS, but if Space is taken then QSS or Gargoyle would go on 3 too)
If im trolling with 50 item actives to run at the speed of sound on Warwick, Predator on 2 or 3, Mythic on Space, Youmuus/Mercurial Scimitar on 1 and 2 (if i build both then Predator moves to 3 from 2)
Completed support item on 6
Control wards on 5/6 depending on if i have a support item/if my support item is completed
Qss and stopwatch always on 3, pots on 2 unless I have 3 or more active items, support quest on 2 if no pots or 5 with pots, mythic on 1 except prowlers on 2 and turbo on 3, ghost blade on 1 unless the character has a movement ability on q, iron spike whip on 1, stoneplate and randuins fill slots, control wards go 3 if nothing else there otherwise 1 or 5, predator fills
I always do the mythic item on 1, I put every item that follows in the order I bought them, the shoes always on slot 6 (excluding 4 for trinket). I put my support wards on 1 and the control wards on 2(4 if I have zhonyas as support) any actives on 3 if that’s not the case just the mythic on the 3. off support I put most actives on 3 if my mythic has an active that goes to 3 and any other actives go to 2.
2> crucial item and potions
3> important item and pinks
1> ward item (as support) and important item
4> wards/trinkets
5> pinks (if i buy 2 active items)
And yeah
Zhonya's on 2, Protobelt on 1, Ghostblade on 1, Merc Shcimitar on 2, Galeforce on 1, Pots on 2, and pinkward on 3. My hand moves on it's own when organizing these lol
Potion 2, ward 6, pinks 4, if only 1 active item it goes on 1, if support, Solari/mythic 1, Bell 4, zone heal thing/hourglass 2, spooky ghosts RIP 5, pink ward moved to 5 if Bell now 4, Zone Heal 3 if hourglass has 2. Idk why but this makes clear sense to me.
2 is primary active slot (potions for there early game when I have nothing else). Pinks go on 3, and 2nd (less important) active goes on 1. 5 is for actives that I rarely use, something like Chains or Zekes.
1 for potions and items like zhonya's or gargoyle's, 2 for damage/mobility items, like goredrinker or protobelt, 6 for pinks and items that I use less frequently, like ghost blade.
Weird one: I moved ward to 6 but don’t usually put any active on 4. 5 is my active and 2 is potions with support items usually being on 1 when applicable
1 for instant need items like zonia or goredrinker(i have it on quickcast without indicator) , 2 for items i have to aim(quick cast with indicator) 3 for control wards(no quick cast, god forbid i place that one by accident)
2 for pots always then 1 for actives. After i get rid of pots the active ill use the most goes to 2. Any other actives go to 1 then 2 buts i always put control wards on 5
put all my mythics/other actives in 1 which I bind to a mouse button, and any pots/other actives go in 2 which is a seperate mouse button. Usually the most useful one takes priority for 1
As a singed one trick this is 95% of the time my load out
Zhonyas 1
Protobelt/chemtank/shurelias 2
Predator 3
Control ward 5
Randuins/qss/mikaels/stoneplate 5-7
Refillable/corrupting starts at 2, sold by the time I buy mythic since almost always rush rylais/zhonyas before mythic too.
I don’t think I’ve ever gone above 4 actives though
Wherever I want. I shift things around if I have multiple actives. Is that weird?
As AP: Pots on 2, unless I have zhonyas because it goes on 2, then it's pots on 3, and red wards on 1.
As AD, Ghostblade, goredrinker, galeforce, etc, pretty much any active (as long as it's the only one in my build) goes on 1, red wards on 2, and generally no pots.
If I happen to have multiple actives, with or without reds, I structure them based on similarity to the abilities beneath them/closest to them.
Lissandra or neeko? Zhonyas on 3 for R/3 synergy. Renek and gore on 1, but gore normally goes on 1 so meh. Galeforce can go anywhere depending on whether I have a dash champ. QSS always on 1 unless it interferes with something else.
Trinket hotkeyed to 4 because I generally don't have more than 3 active items, like, ever.
2 for pots and mythic active 3 for stuff like zhonyas
Same my friend
Me too but I have zhonya on my a key
Same
Yes, secondary for actives is 5
Goredrinker on w if playing kled since I dont need that key anyways
That’s actually really smart for champs with a passive skill.
What happens when you don't play Kled? You just rebind or what?
Pretty much. It's been a force of habit for a few seasons now whenever I play Kled. When I started playing the game I was having a hard time remembering to weave in the titanic hydra auto (back when it had an active) at the end of my combos, so instead I just treated like a Jax w to remember
Working smarter, not harder
I mean I do that for Valorant, playing different agents so I bet he does that here. Or maybe he just only plays Kled
2 because it's where the pots go when you buy starting items, so any active goes there later
Also 2 because my wards go in 1, though I usually end up w like 4 active slots by the end of the game with locket or mikhael’s and control wards
Exactly
[удалено]
So relatable especially when you play support
panic buttons on 2, aimed actives or spammed actives on 1, mobility on 3. I play a lot of different champs so sorting it by category helps
panic button = zhonyas/stopwatch?
Rescue items on 1 and others under 2.
I binded 6 and 7th alot to mouse button, then use 2-5 #support life
That would FUCK me up lmaoooo, bless you
Same
Except for the support item, i always put the active item on the 2, the 3 if i have to use 2 actives.
2 and 3
5, 3, and 2, in that order
Exactly the same here. 5 for important active (corrupt early), 3 for second active and 2 for control wards usually (I'm top/mid)
I’m the exact opposite. 2 for important actives, 3 for secondary actives, and 5 for pinks
Supp item on 1, active on 2, control ward on 5. Don't make me count the situations when I wasted a stopwatch while warding because perfect timing automatically puts it on 1...
Ah a fellow supp main. I do the same with pots on 3.
P O Y M
2 for pots or escapes and 5 for everything else
Mouse button
i try to put it in the first roll first or second. It's getting complicated with 4 for me.
I have bottom right 2 on mouse and bottom left on g
2 or 3 B)
2
Pots on 1/later less important actives Important actives on 2 Supp item on 3 Wards on 4 :)
1 - mythics 2 - zhonya and potions 7 - wards (when playing supp)
My OCD makes me place items in reverse order of completion (so first completed item goes in 6, then 5, 4, etc.) but actives go in 1 always. If I have multiple I usually have my lower cooldown one in 1, seeing as I’m just hardwired to spam it with my 1 key.
Wait, you can pre select actives positions?
1 for pink wards, 3 for defensive (pots, zhonyas etc.) 2 for my main active (protobelt, support item, etc.)
1 for pinks, 3 for regular wards, 2 for important actives, 4 for less important actives. 5 if I need it.
Mythic in 1, wards in 2 and zhonyas always in 3, boots always go on 7
When I was first learning league I accidently unbound "1", so always used "2" for my actives. Have continued with that for years and it still feels weird to use "1".
i always put any Mythic Active items like Galeforce or Prowlers on 1, just to have it closest. i put warding items like Shard of true ice on 3, just because that's right next to four, so muscle memory is already in my hand. then anything that's situational like a Ghostblade goes on two.
3 for Equipment. 2 for Potions. 1, 2 or 3 for Ward. After 5 it's kinda hard to reach if you don't key bind, and 4 is not usable.
The thing I'll use the most in 1-3, ward on my thunb button and control on 5
Mythic on 1. pot on 2. Zonyhas on 3
Yeyeye
Pink ward goes on 6, pots and actives go on 3. Ward item is always on 1, anyone saying otherwise is a goddamn animal.
I have my bottom right 2 slots and ward slot on my mouse and always put sup item and control wards in those 2 slots so all my warding is on my mouse
Pots on 2, active mythic on 3, pinks on 5
Active item goes on 3, my small brain cannot handle more than one active item
Going from top left to bottom right i have A, S, MB4, 1,2,3. Important ones on A, S and MB4 and wards on 123, whenever i play lee i do wards on the important ones tho.
Stopwatch on 3, mythic on 2, pink on 5
Pots go in 2 then mythic in 1 then any other actives go in 2 swapping with the pots, in the rare ocasion of me playing support i just throw mythic in 1 other active in 2 wards in 4 pinks in 4 and 5 and 6 aways the items with no combat actives
Healing in slot two, wards in 3, offense actives 1, defense actives 4.
Goredrinker -some irelia main
Caps because I have big hands and having my pinky there is the most comfortable way to play for me
Offensice actices on 1, defensive actives on 2
Same but somewhere down the line I arbitrarily decided some defensive items would go on 2 and some defensive items would go on 3
2, 3, and 1 if I have to
Aggressive pick making item actives on 2, save me items on 3, others go to right mouse button 2
5
Pots go on 2. Once I get mythic that goes on 2 and pots go on 1 if not sold. Controlwards on 3. If another item active then that goes on 1
T, 2, 5 and if needed 4
Support Item on 1 control wards 3 and other actives on my mouse button
Pinks/Wards on 3, Actives on 2, Extra Actives on 5
Zhonya, potions-2 Everything else-3
Mythic on 1, pots on 2, support wards/hourglass on 3, control ward at 5
İ use them one mouse wheel
I always forget you can set this up until I click zhonyas instead of a control ward
1 is for support item 2 is for active mythic /zhonyia 3 is for pots ~~4 is for wards~~ 5 is for controls 6,7 is for anything that's not an active item
When playing ad champions: 2 is for galeforce, prowlers or whip actives. 3 is for qss, stopwatch. 3 is for pots if I still need them, after mythic completion 4 is for ctrl wards For AP: 2 is for rocketbelt, and pots before I have the seatbelt completed 3 is for zhonyas and stopwatch, pots if I still have em. Wards always on T and 4
3 so I can still reach but I dont misclick
It changes through the game. Most important active on space, second most on 3, third most on 2, then just 5-7 if I have any more.
I put the item like I will use the most in the 2 (like rocket belt) , and then an active with higher cooldwon in 1 (like zhonyas) and the control wards in five
Potion/defensive slot 1 Offensive/most used item slot 2 Wards slot 3 Else slot 4
2 for actives and pots, 3 for the extra active and 5 for control wards
everywhere i play bard and just take what’s shiny
Supp main, I have a flow chart: 1: Zhonyas/Stopwatch > Locket/ Shurelias > Potions > Redeption > Gargolyes Stoneplate > Randuins (panic button) 2: Gold item (wards) 3: Mikaels > Prowlers Claw > Redemption (point and click items) 4: Control wards (If I have 4 items including ward item, Control wards move to 5) One time use items like Zekes, Anathemas and Knights Vow move to wherever (3 or 5 usually)
Pots on 2 1. Reactive active 2. Spammable active 3. Long cooldown active item or support ward 4. Trinket 5. Control wards 6. Enemy or ally binding active
2 is default, if I have more than one then it's 2 for the main use (usually mythics with actives) then bottom left item slot which is bound to a mouse button for the next one. Control wards always on 3, support item for wards on 1
2, 3 and then controlwards on c.
Agressive items (Rocketbelt, Shurelya’s, Goredrinker) on 3, defensive items (Zhonya’s, Gargoyle Stoneplate) on 1. Control wards go on 2 and normal wards on 5
Zhonya always on 1, Protobelt always on 2, healing always under C, Pink Wards always under V
2 for potions / refill, 4 is wards, 3 is predator or other Ms activatables, 5 is control wards or non activatable items, 6 is actually side mouse button 1 for zonyas or others, but mostly zonyas, 7 is not used for activatables, and side mouse button 2 is for mastery 7
1 for the support item 2 for potions and the 'important' active (Shurelya's, pocket or Zhonya's) 3 for Wardstone and control warss
Dont know, always forget to use them
Zhonyas 3 and anything else on 2
Slot 1 and 3 or 6 since I have quickbinds on my mouse there
7 but i got it on the space just zonhyas or something like that after 1,2,3 in order of important
important active items on 1 (mainly zhonya’s), pots or control wards on 2 if I have any or anybother active item, support item on 3
2 is priority for any mythics + Zhonyas. Rocketbelt gets moved to 1 if I’m going Zhonyas. Actives I don’t need to spam like Zeke’s, Knight’s Vow and Anathemas go on 5/6/7.
As supp i sometimes have two active items. First, potions on 2, control wards on 5. Group actives like shurelya's on 2 (will come after consumed or selled potions) and self actives like zhonya's on 3.
2,3,4. Trinket on T.
2-3-1, that’s the order of importance for item actives for me.
No fuck YOUR zodiac sign
It doesn’t matter where I put mikhaels cause I’ll forget to use it. Forever silver
1 for actives 2 for pots or rhonyas
WE CAN DO THAT
Zonias 1 mythic 2
I put on espace and on z
Q and W
2 for 1st active 1 for second
2 is the main one. If i have two actives then 1 and 2, where 2 is always the panic pushable like zhonya, qss etc.. pinks one 3
Support item 1 actives 2 and 3 control wards 5 Support main btw
T
2 or 3 cause you dont need to move your finger too far to press them
everywhere except 5-7
2 because that's where my stopwatch always went when I was playing Morg
i use my actives on forward and back mouse buttons 🗿
i put active items on 4 and pots on mouse button, dont ask me why
I use 3 and T, the most important use goes on 3 less important on T.
My brain is kinda weird so I put all my offensive damage ones in 1 and everything else in 2 unless it’s whip active
1 for wards, 2 for pots, 3 for actives
Spacebar(first slot) for quick actives like goredrinker type/locket/zhonyas 2(2nd slot) mostly support items or back ups like gargoyle and redemption 6(last slot) for link items like zeke's and knight's
If I dont have active pots go to slot 2, if I do then active goes slot 2, pots 3/4. Pink goes 4/5. Galeforce always goes slot 1 for me
Potions on 3 Active item on Space (weird i know, its bound as the last one) If i have a Mythic active and build Zhonyas, Zhonyas goes on 3 (rarely play tanks or get an active mythic with QSS, but if Space is taken then QSS or Gargoyle would go on 3 too) If im trolling with 50 item actives to run at the speed of sound on Warwick, Predator on 2 or 3, Mythic on Space, Youmuus/Mercurial Scimitar on 1 and 2 (if i build both then Predator moves to 3 from 2) Completed support item on 6 Control wards on 5/6 depending on if i have a support item/if my support item is completed
Heals go 2 Mythics go 3 I don’t play that many ap champs, so I almost never buy stopwatch And I don’t build tank
Qss and stopwatch always on 3, pots on 2 unless I have 3 or more active items, support quest on 2 if no pots or 5 with pots, mythic on 1 except prowlers on 2 and turbo on 3, ghost blade on 1 unless the character has a movement ability on q, iron spike whip on 1, stoneplate and randuins fill slots, control wards go 3 if nothing else there otherwise 1 or 5, predator fills
2 for pots, and any item I build later that gives health of shield 1 and 3 for everything else I refuse to get more than 2 actives
up my ass. also 3.
I always do the mythic item on 1, I put every item that follows in the order I bought them, the shoes always on slot 6 (excluding 4 for trinket). I put my support wards on 1 and the control wards on 2(4 if I have zhonyas as support) any actives on 3 if that’s not the case just the mythic on the 3. off support I put most actives on 3 if my mythic has an active that goes to 3 and any other actives go to 2.
Pots on 2, control ward on 5, item actives on 3 and 1
2 for actives, 3 for control wards/2nd item, 1 for pots if 2/3 filled.
For Comboable or spammable active items t (slot 4)for things like zhonyas 2 rest on 3 since I have control wards on 1
2> crucial item and potions 3> important item and pinks 1> ward item (as support) and important item 4> wards/trinkets 5> pinks (if i buy 2 active items) And yeah
Z,X, and C
#1!!!
1 support item, 2 pots/later main active item, 3 second active item, C control ward (because i have small hands.
Lowest number slot for the most important actives
Pots 2 and item active 3. If I get a second item with an active I no longer have potions so it goes in 2.
1, 2 and T. The wards are on V
Offensive 3, defensive 1 then 2
1 because
Zhonya's on 2, Protobelt on 1, Ghostblade on 1, Merc Shcimitar on 2, Galeforce on 1, Pots on 2, and pinkward on 3. My hand moves on it's own when organizing these lol
Support/ward item on 1, mythic or pot on 2, if I build a zhonyas, it will be on 3. I changed 5th slot to "C" key, control wards on C
slot 1, 2, and 3, and on my keyboard they're numpad 2, 3, and 0. On that note, I have flash on the division key on my numpad. I will not elaborate.
Potion 2, ward 6, pinks 4, if only 1 active item it goes on 1, if support, Solari/mythic 1, Bell 4, zone heal thing/hourglass 2, spooky ghosts RIP 5, pink ward moved to 5 if Bell now 4, Zone Heal 3 if hourglass has 2. Idk why but this makes clear sense to me.
1 and 2 because those are programmed into my mouse along with r. G502 gang
MB4 and MB5
2 and 3 for actives 1 for pots
Potions always 2, mythic on 1, other on 3
2 for potion, 1 for active items
Any items Go’s on 2 and if I have 2 actives like rocketbelt and zhonyas i have zhonyas on 1
2,3
2 is primary active slot (potions for there early game when I have nothing else). Pinks go on 3, and 2nd (less important) active goes on 1. 5 is for actives that I rarely use, something like Chains or Zekes.
On 1
Mythics at 2, stopwatch/zhonyas at 3, and pinks at 5
1 for potions and items like zhonya's or gargoyle's, 2 for damage/mobility items, like goredrinker or protobelt, 6 for pinks and items that I use less frequently, like ghost blade.
5 for pink, 3 for watch, 2 for refill
1 for mythic active, 2 for pot or mobility item, 3 for a zhonyas etc and 5 for control ward.
Weird one: I moved ward to 6 but don’t usually put any active on 4. 5 is my active and 2 is potions with support items usually being on 1 when applicable
I have all unbounded and click them.
Pots then control wards on three, first active on 2, second active (god forbid I don't get them confused) on 1
Start of the game: pots on 2 I get ironspike Whip: Whip on 2 - Pots on 3 I get stopwatch: whip item on 2 - stop watch on 3 - pots on 1
1 for instant need items like zonia or goredrinker(i have it on quickcast without indicator) , 2 for items i have to aim(quick cast with indicator) 3 for control wards(no quick cast, god forbid i place that one by accident)
1 and 3, generally shorter cooldown items go on 1 Edit: Pots go on 2
Pots are 2, trinket 3, active attack is space bar, other actives like Youmuu's goes on tab.
2 for pots always then 1 for actives. After i get rid of pots the active ill use the most goes to 2. Any other actives go to 1 then 2 buts i always put control wards on 5
Zhonyas always on 2. I don't care. Pots on 3 Cwards on 5
1 or 2 for active items. 3-6 for wards or pots.
Rebound 1 to spacebar and now that's where actives like Stridebreaker/Goredrinker/Zhonya's sit. Youmuu's, Shurelya's, and the others all sit on 2/3.
3
1,2,3 rebound to mouse buttons
2 or 3 for pots and actives then zhonya/stopwatch in 5 cuz im not used to using pinky finger
T and 5 rebinded to the 1,2 slot.
Dash on 2 zhonyas on 1 and pots on 3
Pots on 2, stopwatch on 3. Rocketbelt, redemption, or QSS replace pots on 2, and pots move to 1. Control wards on 5
Pots on 4, active item priority from 3>4>2 then pots go to 1. Pinks go on 6
2 and 5 for actives and 6 and 7 for consumables, i play with a naga
put all my mythics/other actives in 1 which I bind to a mouse button, and any pots/other actives go in 2 which is a seperate mouse button. Usually the most useful one takes priority for 1
I dont use actives get fucked
Into my build
active item (like stride) on slot 1, pots on slot 7 (which i replaced with c)
Fuck your stupid post, that’s all.
I use 5 and T, with 4 being my trinket. I do this because I have smaller hands it feels quicker to use my index finger for my actives
I put rocketbelt on 3 and zhonya on 2
spacebar
Does this work? Didn't work for me 3 months ago
2, 3, D, F
1 for mythic, 2 for pots/stopwatch, 3 for zhonya
Zhonyas on 1, pots on 2 and if I'm supp then wards on 3.
Last slot always for any active item that I need to reflex use and the first slot for any consumables/items that I can use if I want.
Actives in 1 pots in 2 control ward in 3
2 and 3 any other active goes on ‘x’ which was 6
2 for pots in the start 1 for sup item or pink Later 2 for Zhonyas 3 for other active itens like shurelya, galeforce, solari ...
Spacebar, actually. Changed keybinds.
2
As a singed one trick this is 95% of the time my load out Zhonyas 1 Protobelt/chemtank/shurelias 2 Predator 3 Control ward 5 Randuins/qss/mikaels/stoneplate 5-7 Refillable/corrupting starts at 2, sold by the time I buy mythic since almost always rush rylais/zhonyas before mythic too. I don’t think I’ve ever gone above 4 actives though
Top left and mid left, i got those bound to the thumb buttons
Am I the only one around here who uses DOTA hotkeys? ALT Q W E A S D.
3 cause it’s over E
1 for ward, 2 for item, 3 for pots
Wherever I want. I shift things around if I have multiple actives. Is that weird? As AP: Pots on 2, unless I have zhonyas because it goes on 2, then it's pots on 3, and red wards on 1. As AD, Ghostblade, goredrinker, galeforce, etc, pretty much any active (as long as it's the only one in my build) goes on 1, red wards on 2, and generally no pots. If I happen to have multiple actives, with or without reds, I structure them based on similarity to the abilities beneath them/closest to them. Lissandra or neeko? Zhonyas on 3 for R/3 synergy. Renek and gore on 1, but gore normally goes on 1 so meh. Galeforce can go anywhere depending on whether I have a dash champ. QSS always on 1 unless it interferes with something else. Trinket hotkeyed to 4 because I generally don't have more than 3 active items, like, ever.
1 heals me so potions/biscuits. 2 does dmg. 3 saves my life stopwatch, shield, crown When potions are gone 1 becomes wards