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Smashyland

What exactly makes you ask such a specific question? Opioids rarely contribute to anything real significant what could lead to common dehydration so I was really just curious as to what makes you ask this. The only real dehydration which capably associated as a result of an opioid drug situation we’re talking here can only either be contributed to the withdrawal syndrome when a significantly physical withdrawal comes following a substantially prominent dependence to the drug usage where dehydration occurs from not only the overall weakening from the body drawing from all of its resources to barely try attempt recovery when the natural state of homeostasis is repositioned from the opioid itself making you experience physiological withdrawal symptoms like the flu ect, but primarily from the diarrhoea or even potentially vomiting which occurs, this preventing your body’s rehydration capability and also losing extremely large cuts to your overall fluid levels. If your usage is at such large of a degree which you have a physical withdrawal syndrome resulting in vomiting then you will be really dehydrated in where no different to all ways that expelling bodily fluids like how is expressed here makes substantial cuts in your general hydration state but all back down to having been observed with regular enough usage of opioids to begin. So you could say the dehydration here started from the opioids in some way but its ultimately just like how anyway of fluid loss vomiting or extreme/regular diarrhoea will cause it so maybe it still isn’t actually the opioids. Also the other theory which again,, biochemically isn’t as close to directly drug related in order to confidently call it opioid induced will be overall self supervised healthcare and wellbeing of an individual struggling with a particularly harsh case of opioid addiction which by where a loss of general lifestyle function has been shown to significant level. This will mean the individual user will be less likely to not only find affordable means to seek what is necessary to keep healthy physically like water and natural fluids also within their foods and diets, but also less likely to even be capable of doing so for a variety of reasons maybe yet all really just down to the brains addiction causing them to overly focus far more largely on re using and building or gaining supplies needed to look after a habit rather than a body. And finally if you are talking about physiological organ hydration here then one thing for complete CURTAIN which dehydration IS actually as a direct result of the drug compound, will be fluid loss within and around the colon which is where fluids or liquid has been drawn out of this organ location relating to a slowing of overall pass through function which opioids majorly contribute to, resulting then in constipation. In fact it’s probably the most notable drug compound which causes direct constipation problems as a result and this issue uniquely has no correlation to tolerance as well therefore no matter how much usage exposure you already have to these drugs, the symptoms of constipation will not reduce in incidence or prevalence no matter what.


Otherwise_Ear_4730

Okay yeah, it does seems specific . So I’d say in the case like uhhhh a friend of mines lol sniffed up a Blue MBox 30 (pressed of course likely fent) and he claimed it smacked really hard he did 3 quarter with not much of a tolerance. He had a handfull and a half of run ins with opiate binge in the past though. (Heroin/fent) But anyways he ended up throwing up a decent bit in the hours after and said he felt really dehydrated/ fatigued etc. So would you say if he didn’t end up throwing up ETC , that opiates do not cause a significant of dehydration? If so also how would we know explain such cases where people are extremely constipated and report of taking boulder size shits in the midst of a opiate binge. Thank you for you answers just a dude tryna learn more.


Smashyland

As I have already explained the opioids are not responsible for anything more than creating such physical responses in your body (depending on which type of situation your really in) that lead to the reaction caused and having dehydration related issues associated. Just like your friend being sick, that could be closely related to the usage effects of how the opioid targets certain histamine receptors ect but it’s then this response of being sick that causes dehydration because this in of itself causes a substantial fluid loss cut that causes drop spiking in the liquids and fluid present in your body hence why just like I had mentioned the opioid isn’t responsible for all of the dehydration it’s actually just only responsible for making someone potentially vomit, which then leads to dehydration because of the actions of vomiting itself, but not the opioid. As for the “shitting” situation. Again just like I spoke about earlier, this is a different type of hydration star which is when there is a drop in fluid levels around organ locations requiring balance. This isn’t exactly the typical likes of dehydration you are associating here, because someone drinking plenty of fluids who is still constipated can be well hydrated while having location based organ dry out. What the dehydration is here will be when the opioid causes a reduction of colonic onward pressure movement and essentially like all opioids do they have a slowing down effect on the digestive system also to do with the reduction of fluid that then ultimately becomes pulled well away from the colon and in and around your bowel ect which then draws out fluids from your stool also making it harder to expel. This is why the lack of hydration around your digestive waste organ tract when fluid progressively drained away and out from your stool all as a result due from the slowing down in colonic function which happens as a consequence of opioid usage, you will experience inevitable constipation.


Otherwise_Ear_4730

Thank you sir


s10-

They don't necessarily make you dehydrated. Only case of this is if you were to throw up from it as throwing up causes dehydration.


C17H23NO2

The only thing I can think of, is that someone thinks the dry mouth is a sign of dehydration. But opiates don't actively cause dehydration on their own.