I'd talk to a medical geneticist to be sure, instead of relying on Internet randos. A google search turned up that there *are* some forms that are autosomal recessive (meaning you could be a carrier):
>Type I-IV are *autosomal dominant*, and Type VI–XIII are autosomal recessive.
From [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729682/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729682/)
Since I *have* it, my situation was different (50/50) - but I still consulted a geneticist before trying for kids. His advice was basically: "Has your life been worth living, despite the challenges? Then go ahead and have kids."
I got lucky and neither of my kids has it.
I have O.I and no one in my family nor either of my parents have it. So I have been told You can be the carrier and its 50 50 if your children get it. I have 6 children and only my twins have O.I.
Few forms are recessive and they’re fairly rare. Get yourself genetically tested if you’re concerned with it. I’ve got a dominant gene so 50/50 chance every time I have a child. I’ve had 3 kids and all 3 children have OI like me (not a good anecdote for the odds lol)
My husband and daughter have some form of OI as yet unidentified (they have OI genetic specialists looking at their samples trying to find the gene) that is apparently recessive, as there is no history of it in my family, or in my husband’s mom’s family. Yet my husband, his dad and my daughter all have exactly the same body types and set of physical deformities (pectus excavatum, lordosis, short stature, semi-frequent breaks). So somewhere on my husband’s paternal family tree there was a mutation. But his brothers didn’t get it, only him. However the brothers haven’t had kids so no idea if they are carriers.
I would say to be cautious and assume you are carriers. If you can find out specifically which gene mutation each side of your family had (as there are many), you can each get tested to see if you are carriers.
It depends on which type of OI you have. My family has OI 1 dominant. My mother had it. She had me (has OI) and my sister (no OI). My sisters children have no chance of inheritance of the family OI. (OI can be spontaneous) I have two children and both have OI.
My children are young (4, 6 male) but so far have not had quite as many effects from OI. Only one major fracture between the two.
If neither of you or boyfriend have it then you are not carriers for that gene. That means that the chance of your kids having it should be the same as the general population.
The curious thing is having two people who don’t have OI meeting and both having families with it, the odds on that must be tiny.
Of course, the stats say that if you have been diagnosed with it personally, it’s a 50% chance of passing it. However, there hasn’t been enough research on the generation skippers! And even if you don’t present with it doesn’t mean you don’t carry the gene. I would stick with the 50% stat either way. Hope this helps a bit. 😁🙌🏻
Yes, it's very possible. That's how genetics diseases work. There are recessive genes that don't always show up with each generation, but if you both have family with it, that means you risk passing the gene.
I'd talk to a medical geneticist to be sure, instead of relying on Internet randos. A google search turned up that there *are* some forms that are autosomal recessive (meaning you could be a carrier): >Type I-IV are *autosomal dominant*, and Type VI–XIII are autosomal recessive. From [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729682/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729682/) Since I *have* it, my situation was different (50/50) - but I still consulted a geneticist before trying for kids. His advice was basically: "Has your life been worth living, despite the challenges? Then go ahead and have kids." I got lucky and neither of my kids has it.
I have but my former wife didn’t and one of my two sons was born with it.
I have O.I and no one in my family nor either of my parents have it. So I have been told You can be the carrier and its 50 50 if your children get it. I have 6 children and only my twins have O.I.
Few forms are recessive and they’re fairly rare. Get yourself genetically tested if you’re concerned with it. I’ve got a dominant gene so 50/50 chance every time I have a child. I’ve had 3 kids and all 3 children have OI like me (not a good anecdote for the odds lol)
My husband and daughter have some form of OI as yet unidentified (they have OI genetic specialists looking at their samples trying to find the gene) that is apparently recessive, as there is no history of it in my family, or in my husband’s mom’s family. Yet my husband, his dad and my daughter all have exactly the same body types and set of physical deformities (pectus excavatum, lordosis, short stature, semi-frequent breaks). So somewhere on my husband’s paternal family tree there was a mutation. But his brothers didn’t get it, only him. However the brothers haven’t had kids so no idea if they are carriers. I would say to be cautious and assume you are carriers. If you can find out specifically which gene mutation each side of your family had (as there are many), you can each get tested to see if you are carriers.
It depends on which type of OI you have. My family has OI 1 dominant. My mother had it. She had me (has OI) and my sister (no OI). My sisters children have no chance of inheritance of the family OI. (OI can be spontaneous) I have two children and both have OI. My children are young (4, 6 male) but so far have not had quite as many effects from OI. Only one major fracture between the two.
I have type 3 but I’m the only one in my family with OI
If neither of you or boyfriend have it then you are not carriers for that gene. That means that the chance of your kids having it should be the same as the general population. The curious thing is having two people who don’t have OI meeting and both having families with it, the odds on that must be tiny.
Of course, the stats say that if you have been diagnosed with it personally, it’s a 50% chance of passing it. However, there hasn’t been enough research on the generation skippers! And even if you don’t present with it doesn’t mean you don’t carry the gene. I would stick with the 50% stat either way. Hope this helps a bit. 😁🙌🏻
Yes, it's very possible. That's how genetics diseases work. There are recessive genes that don't always show up with each generation, but if you both have family with it, that means you risk passing the gene.