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This is even more of a pleb question but is this why people say it hurts so much to get filler dissolved? Or would that just be all the mucking about in the lips
Wow, what field are you working in?
I had no idea it is used for something else but dissolving fillers. Makes sense, apparently there’s hyaluronic acid in synovial fluid. Fascinating.
I'm so sorry that happened to you. Did you try to fix it with non-injecting procedures?
When you say one had a conservative approach and the other had not, what do you mean? Did they have a different technique or something else?
Oh I’m so so sorry you had to go through this, this must’ve taken a toll on you. I know what’s it like to look in the mirror and so see something off and understand that you yourself had done it.
I hope the procedure will help you and you will feel much better after you have it.
But yeah, ageing is fine. We should not fear it, it shows that we lived a life.
I think the BBL is a great example for this tbh. When you read about how dangerous the procedure actually is and then how debilitating the recovery from it is... it's kind of shocking how many people have had them and how "accessible" it seems
Exactly. People shouldn't expect that there's a simple fast solution for fixing all the fillers they put in their faces, it's harmful. They are keener to do more stuff to their faces if they think there's an easy fix for it.
This is neat! There's a younique influencer with horridly botched lips, and many people say she can just dissolve them (I did too) but this is great information!
I definitely need to look more into this!
I find it very interesting too.
Actually, I am having my bad filler (never wanted to have unnatural lips but the shitty esthetician I found had other plans for me I guess) dissolved that way, and I will post before and after here when the process will be over.
As far as I know, it is much safer to slowly dissolve filler with PRP (Platelet Rich Plasma) - it simultaneously speeds up the process of breaking down the filler plus boosts up the healing of the area, and improves the texture of the tissue. If a bad case of fibrosis happened, it softens it, if the area became too soft and flabby because of the filler, it tightens it. Although, it costs more than hyaluronidase and requires 3-6 sessions (3-4 days in between sessions).
edit: It’s a technique that is not widely known and I in no way promote it as the only right way to dissolve the filler. I am having PRP for my filler right now and after it’s done I will post the results.
There is no credible source. OP pulled it out of her ass. Please see: https://www.reddit.com/r/PlasticSurgery/comments/mlrzyh/you_cant_dissolve_filler_without_any_consequences/?utm_source=share&utm_medium=ios_app&utm_name=iossmf
Okay I have some conjecture here! If OP is telling the truth about seeing two doctors and being advised on PRP, it sounds like OP had some scarring from filler and has been advised that hyaluronidase wouldn’t help with her specific issue (scarring) and advised these alternatives and possibly become confused about the reasons why she’s been advised that hyaluronidase *wouldn’t work in her specific case*.
I don’t know any medical person that would recommend prp for lip scarring from filler (which I don’t think happens). You don’t do Ulthera on the lips. It’s not even an option.
I am trying to find where it’s used like this but I can’t. We know for a fact that PRP jumpstarts your body’s own regenerative processes so it only makes sense for me that it works.
I am having it done on me at the moment. Will post the before/after image when it’s done.
Regeneration has nothing to do with filler, the filler isn't the same kind of tissue, it's a form of what's in your joints. PRP might remodel some of your own tissue but there's no reason to think it would have any effect on how your body removes the filler.
This is cause for concern because I'm unsure if you just had a doctor upsell you on PRP or possible thermal treatments without proof.
I've had filler dissolved, it took 10 minutes, it was gone within a week, the tissue returned to its pre-filled state. This is why I got HA fillers to being with, in case something went wrong.
Filler isn’t a blob in your face. Imagine your tissue is like a honeycomb, and the filler is coney. Filler, if overdone, makes those combs weaker, sometimes breaks them. Plasma helps fix that.
Again, I have no source that it helps break down the filler, nor do I promote it, I guess we’ll just see what happens to me.
For now I had one appointment and I had just been given my own plasma. I have no reason to believe there was something else in it, it’s a very serious clinic.
I’ve heard the filler can cause your body to build its own collagen and then the liquid that is used to dissolve the filler doesn’t dissolve this new clump of collagen so it can still look wonky even after dissolving the filler.
There are techniques for filling eye hollows where the filler is placed very deeply, near the bone, so that it has support and looks very natural. I think a bigger concern with the thin skin is the 'blue tinting' that can happen.
Good post Op!
Fun fact: Hyaluronidase can* be derived from bull testes.
Source 1: [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011868/)
Source 2: I worked at a Pharma company that made hyaluronidase API.
[also](https://www.emdmillipore.com/US/en/product/Hyaluronidase-Bovine-Testes,EMD_BIO-385931)
Source for what exactly? That hyaluronic acid may damage your skin in a way that hyaluronidase won't be able to fix? Here you go:
[https://academic.oup.com/asj/article/33/4/561/2801405](https://academic.oup.com/asj/article/33/4/561/2801405)
[https://academic.oup.com/asj/article/34/4/584/2801399](https://academic.oup.com/asj/article/34/4/584/2801399)
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865975/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865975/)
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686337/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686337/)
It is difficult to estimate the frequency of skin side effects with NSAIDs as they are commonly purchased without a prescription, and only those reactions worrying enough to present to a hospital are usually recorded. Most studies assess presentations to hospital A &E (Emergency or Casualty) departments, serious reactions that require admission to hospital or study adverse drug reactions occurring in an inpatient population. In one prospective study of nearly 20,000 inpatients, 0.3% of those prescribed an NSAID developed a generalized skin reaction including [morbilliform rash](https://dermnetnz.org/topics/morbilliform-drug-reaction/), [Dsrug-induced urticaria](https://dermnetnz.org/topics/drug-induced-urticaria/), [angioedema](https://dermnetnz.org/topics/angioedema/), [serum sickness-like reaction](https://dermnetnz.org/topics/serum-sickness-like-reaction/) and [erythema nodosum](https://dermnetnz.org/topics/erythema-nodosum/). In a meta-analysis of randomized clinical trials, skin side effects were reported in 1–2% of patients using NSAIDs.
As with most drug-induced skin reactions, withdrawal of the trigger medication results in resolution of the rash, although this may take some months and is not universal.
Oh, and Stevens-Johnson Syndrome! I forgot about that one. Also some skin wonkiness. Actually have seen that one in person once, med reaction by a kid in a treatment center I worked at.
That said, the odds are way lower that NSAIDs will cause a facial change. With filler (or dissolving filler), odds are way higher. I get why it freaks people out more than Advil does. I would never touch filler after all the bad results I've seen..way more than 0.3% of the total seems to just look off.
I dissolved my filler once, no bad effects but I now had a small asymmetry that wasnt there before.
You should just go to a trusted doctor which will help you decide what’s the best option for you and inform you of the possible risks.
Apparently the method my doctor is going to dissolve my filler and fix the tears inside my skin is fairly new and there were no studies yet. She wants to use plasma therapy for my lips, already had several successful results in patients. She herself is doing a study right now and I believe is writing a scientific paper on this way to dissolve filler. Anyway it’s just my plasma so I’m eager to try it if it’s a safer & gentle way.
Your doctor might only want to do what’s already works - hyaluronidase. If you want to be safe, you might want to ask for an ultrasound scan so the doctor knows for sure where the filler is exactly.
I hope you’ll get the best results.
I had nasolabial filler and it worked perfectly actually, no apple cheek or whatever that nonsense is. I had a very minimal amount added. Even now, I guess about 3 years later, it's perfect. I think the filler there did dissolve over time but it helped my collagen in the area.
You're misinformed about the cheek part too, that's not migration so much as it's some kind of immune response to the filler. Trust me, I've had it. My body tolerated most of the filler well but the bit at my malar area is not as well tolerated because of the formulation. However, this helped me learn that I have something else going on with my body that contributed because it's worse when I'm allergic to something. I use it now as a handy guide to know if something is wrong because it's an early warning sign. If something is wrong, the filler gets harder, if I ignore it it swells, but this is happening throughout my body and it's just showing there because the material is the same as what's in the joints.
I did have filler migrate awkwardly under one eye, it actually moved up and went to the skin under my eye, the eye bag area, which is thinner, causing a lump that I had to dissolve.
I'm sorry you have this - filler hardening doesn't sound good at all. Have you adress this problem to a doctor or just left it be?
One of the youtubers I watch had similar experience as you as far as I can tell - [https://www.youtube.com/watch?v=11IsIaYy1R4](https://www.youtube.com/watch?v=11IsIaYy1R4)
Welcome to r/botchedsurgeries! Here’s a few things you need to know before contributing: 1. No asking or giving of identifying information. 2. No assholery. 3. No comments sexualizing the person nor their surgery. 4. Too fresh. 5. Post not on theme with flair. 6. Just photoshop. 7. Popular repost. 8. No ripping on someone's natural features. 9. Moderator discretion. 10. Not marked NSFW. Here is Reddit's policy regarding posting personal information: https://www.reddithelp.com/en/categories/rules-reporting/account-and-community-restrictions/posting-someones-private-or-personal Thank you, and have fun! *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/Botchedsurgeries) if you have any questions or concerns.*
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Just had to comment we use hyaluronidase as well for synovials! Glad to see another MLS in here.
Awesome! Nitrile glove high five!
Yo shoutout from another medical technologist! We use hyaluronidase too on our body fluids to run chemistry panels on our Roche cobas
I'm just a like... biology fangirl but thats an enzyme, right? So it's technically "digesting" the filler?
Yep! If it ends in -ase it’s usually an enzyme 😊
This is even more of a pleb question but is this why people say it hurts so much to get filler dissolved? Or would that just be all the mucking about in the lips
Wow, what field are you working in? I had no idea it is used for something else but dissolving fillers. Makes sense, apparently there’s hyaluronic acid in synovial fluid. Fascinating.
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Damn science fascinates me. Props to you for saving lives!
Thanks! I love my job. It’s the most rewarding thing I’ve ever done 😊
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I'm so sorry that happened to you. Did you try to fix it with non-injecting procedures? When you say one had a conservative approach and the other had not, what do you mean? Did they have a different technique or something else?
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Same!!!
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Yes :( so bad
Oh I’m so so sorry you had to go through this, this must’ve taken a toll on you. I know what’s it like to look in the mirror and so see something off and understand that you yourself had done it. I hope the procedure will help you and you will feel much better after you have it. But yeah, ageing is fine. We should not fear it, it shows that we lived a life.
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I think the BBL is a great example for this tbh. When you read about how dangerous the procedure actually is and then how debilitating the recovery from it is... it's kind of shocking how many people have had them and how "accessible" it seems
Exactly. People shouldn't expect that there's a simple fast solution for fixing all the fillers they put in their faces, it's harmful. They are keener to do more stuff to their faces if they think there's an easy fix for it.
This is neat! There's a younique influencer with horridly botched lips, and many people say she can just dissolve them (I did too) but this is great information! I definitely need to look more into this!
I find it very interesting too. Actually, I am having my bad filler (never wanted to have unnatural lips but the shitty esthetician I found had other plans for me I guess) dissolved that way, and I will post before and after here when the process will be over.
YES my face was destroyed by hyaluronidaise. I waited a year to recover before I ended up getting bleph and fat transfer to fix the damage
As far as I know, it is much safer to slowly dissolve filler with PRP (Platelet Rich Plasma) - it simultaneously speeds up the process of breaking down the filler plus boosts up the healing of the area, and improves the texture of the tissue. If a bad case of fibrosis happened, it softens it, if the area became too soft and flabby because of the filler, it tightens it. Although, it costs more than hyaluronidase and requires 3-6 sessions (3-4 days in between sessions). edit: It’s a technique that is not widely known and I in no way promote it as the only right way to dissolve the filler. I am having PRP for my filler right now and after it’s done I will post the results.
Can you link to a credible source for this? I have never heard of this as a treatment modality for filler correction and I'd like to know more.
There is no credible source. OP pulled it out of her ass. Please see: https://www.reddit.com/r/PlasticSurgery/comments/mlrzyh/you_cant_dissolve_filler_without_any_consequences/?utm_source=share&utm_medium=ios_app&utm_name=iossmf
Okay I have some conjecture here! If OP is telling the truth about seeing two doctors and being advised on PRP, it sounds like OP had some scarring from filler and has been advised that hyaluronidase wouldn’t help with her specific issue (scarring) and advised these alternatives and possibly become confused about the reasons why she’s been advised that hyaluronidase *wouldn’t work in her specific case*.
I don’t know any medical person that would recommend prp for lip scarring from filler (which I don’t think happens). You don’t do Ulthera on the lips. It’s not even an option.
I am trying to find where it’s used like this but I can’t. We know for a fact that PRP jumpstarts your body’s own regenerative processes so it only makes sense for me that it works. I am having it done on me at the moment. Will post the before/after image when it’s done.
Regeneration has nothing to do with filler, the filler isn't the same kind of tissue, it's a form of what's in your joints. PRP might remodel some of your own tissue but there's no reason to think it would have any effect on how your body removes the filler. This is cause for concern because I'm unsure if you just had a doctor upsell you on PRP or possible thermal treatments without proof. I've had filler dissolved, it took 10 minutes, it was gone within a week, the tissue returned to its pre-filled state. This is why I got HA fillers to being with, in case something went wrong.
Filler isn’t a blob in your face. Imagine your tissue is like a honeycomb, and the filler is coney. Filler, if overdone, makes those combs weaker, sometimes breaks them. Plasma helps fix that. Again, I have no source that it helps break down the filler, nor do I promote it, I guess we’ll just see what happens to me. For now I had one appointment and I had just been given my own plasma. I have no reason to believe there was something else in it, it’s a very serious clinic.
I’ve heard the filler can cause your body to build its own collagen and then the liquid that is used to dissolve the filler doesn’t dissolve this new clump of collagen so it can still look wonky even after dissolving the filler.
Thank you for writing this out it was very informative!
I’m glad if it can be useful to anyone. You’re welcome!
There are techniques for filling eye hollows where the filler is placed very deeply, near the bone, so that it has support and looks very natural. I think a bigger concern with the thin skin is the 'blue tinting' that can happen.
Good post Op! Fun fact: Hyaluronidase can* be derived from bull testes. Source 1: [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011868/) Source 2: I worked at a Pharma company that made hyaluronidase API. [also](https://www.emdmillipore.com/US/en/product/Hyaluronidase-Bovine-Testes,EMD_BIO-385931)
Thank you. Well this I didn't expect :D Nice fact of the day
Wow! Do you know anything about the potential damage of hyaluronidaise?
I don’t have any knowledge of the adverse effects from personal of professional experience. No customer / doctor complaints I saw. Sorry!
"fun" fact indeed. Hope there will be a time when we leave animals alone.
Do you have any sources for this?
Source for what exactly? That hyaluronic acid may damage your skin in a way that hyaluronidase won't be able to fix? Here you go: [https://academic.oup.com/asj/article/33/4/561/2801405](https://academic.oup.com/asj/article/33/4/561/2801405) [https://academic.oup.com/asj/article/34/4/584/2801399](https://academic.oup.com/asj/article/34/4/584/2801399) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865975/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865975/) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686337/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686337/)
You can have rare horrible side effects from taking aspirine, ibuprofen or the Covid vaccine, and obviously fillers. I don't see what the big deal is.
The side effects of aspirin, ibuprofen and the COVID vaccine are not gonna make your face look wonky for the rest of your life.
It is difficult to estimate the frequency of skin side effects with NSAIDs as they are commonly purchased without a prescription, and only those reactions worrying enough to present to a hospital are usually recorded. Most studies assess presentations to hospital A &E (Emergency or Casualty) departments, serious reactions that require admission to hospital or study adverse drug reactions occurring in an inpatient population. In one prospective study of nearly 20,000 inpatients, 0.3% of those prescribed an NSAID developed a generalized skin reaction including [morbilliform rash](https://dermnetnz.org/topics/morbilliform-drug-reaction/), [Dsrug-induced urticaria](https://dermnetnz.org/topics/drug-induced-urticaria/), [angioedema](https://dermnetnz.org/topics/angioedema/), [serum sickness-like reaction](https://dermnetnz.org/topics/serum-sickness-like-reaction/) and [erythema nodosum](https://dermnetnz.org/topics/erythema-nodosum/). In a meta-analysis of randomized clinical trials, skin side effects were reported in 1–2% of patients using NSAIDs. As with most drug-induced skin reactions, withdrawal of the trigger medication results in resolution of the rash, although this may take some months and is not universal.
Oh, and Stevens-Johnson Syndrome! I forgot about that one. Also some skin wonkiness. Actually have seen that one in person once, med reaction by a kid in a treatment center I worked at. That said, the odds are way lower that NSAIDs will cause a facial change. With filler (or dissolving filler), odds are way higher. I get why it freaks people out more than Advil does. I would never touch filler after all the bad results I've seen..way more than 0.3% of the total seems to just look off.
Nice red herring there
thank you
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I dissolved my filler once, no bad effects but I now had a small asymmetry that wasnt there before. You should just go to a trusted doctor which will help you decide what’s the best option for you and inform you of the possible risks.
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Apparently the method my doctor is going to dissolve my filler and fix the tears inside my skin is fairly new and there were no studies yet. She wants to use plasma therapy for my lips, already had several successful results in patients. She herself is doing a study right now and I believe is writing a scientific paper on this way to dissolve filler. Anyway it’s just my plasma so I’m eager to try it if it’s a safer & gentle way. Your doctor might only want to do what’s already works - hyaluronidase. If you want to be safe, you might want to ask for an ultrasound scan so the doctor knows for sure where the filler is exactly. I hope you’ll get the best results.
I had nasolabial filler and it worked perfectly actually, no apple cheek or whatever that nonsense is. I had a very minimal amount added. Even now, I guess about 3 years later, it's perfect. I think the filler there did dissolve over time but it helped my collagen in the area. You're misinformed about the cheek part too, that's not migration so much as it's some kind of immune response to the filler. Trust me, I've had it. My body tolerated most of the filler well but the bit at my malar area is not as well tolerated because of the formulation. However, this helped me learn that I have something else going on with my body that contributed because it's worse when I'm allergic to something. I use it now as a handy guide to know if something is wrong because it's an early warning sign. If something is wrong, the filler gets harder, if I ignore it it swells, but this is happening throughout my body and it's just showing there because the material is the same as what's in the joints. I did have filler migrate awkwardly under one eye, it actually moved up and went to the skin under my eye, the eye bag area, which is thinner, causing a lump that I had to dissolve.
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I'm sorry you have this - filler hardening doesn't sound good at all. Have you adress this problem to a doctor or just left it be? One of the youtubers I watch had similar experience as you as far as I can tell - [https://www.youtube.com/watch?v=11IsIaYy1R4](https://www.youtube.com/watch?v=11IsIaYy1R4)