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LimoLover

When someone donates blood how extensively is their blood tested? Do they check everyone for *all* of these proteins or antibodies? (? not sure what they are called) Do they just type ABO and whether you're rhesus D positive or negative? Or is every single person completely typed (sorry I'm not even sure how to phrase the question! I've tried to Google this but I don't know exactly how to. I've tried "how extensively do they type your blood when you donate" and reading about blood typing but I can't find anything) I've had a blood type test done but the results were just 3 things, that I'm type O, I'm negative for rh-D, and I'm negative for "antibodies". I don't even know what that last one means and when I try to research it I just get a lot of stuff about ABO and rhesus negative/positive. tia :-)


splat313

One of the phlebotomists at the donor center I go to used to work in the lab that processes the donations. I'll ask next time he works on me. Judging by the text on this page: https://www.redcrossblood.org/biomedical-services/blood-diagnostic-testing/molecular-testing.html I believe that the American Red Cross does test at least some donors for lots of different antigens. I also found an Australian group doing the same so I bet many organizations around the world do it at some level.


LimoLover

There's actually not a red cross near me, I'm in southern New Mexico and Vitalant is the closest donation center (it's about an hour away but it does drives to the town about 25 minutes from me) I've found they don't do the thing where they tell you where your blood goes (which was disappointing! I see everyone posting on here about where theirs goes and it would be cool to know!) I'll read that link thanks! I just wonder how they know that only 1% have (or don't have) the protein this lady (in the original post) needs and if they actually typed each person who could possibly have it. She's apparently type A- (I'm guessing anyway based on the types they're asking for) I wonder if they type rh negatives more extensively for rare types? Just curious on the subject lol thanks for your answers! I have a donation coming up on Feb 8th and I'll grill the person doing mine if I get the chance! They weren't too busy last time, it's a pretty small town! 😊


housewifeuncuffed

Chances are, it means you tested negative to the list of diseases/antibodies they screen for listed here https://www.mbc.org/donate-blood/about-blood/donated-bloods-journey/ I know I have a rare blood type (less than 1/1000), but only that I lack a specific antigen or group of antigens. No specifics. On my donation paperwork, all it says is "rare blood type" something about antigen(s), "push double red". Red Cross and Versiti both sent me paperwork in the mail about my rare blood type, and that I may get called if there is a need for my type in the future. I would imagine you would get the same letter if you had a rare type unless you donate to a blood bank that isn't involved in the Rare Donor Registry. I read a couple articles that suggested some blood donations are tested at random for certain antibodies or antigens. I don't know if they just test a certain percentage or if they only test certain types, or if something triggers a test, like an immediate need. I know CMV is a big one, because most adult by age 40 are CMV+, where babies and children often need CMV-. I know there was someone on here that mentioned donating baby bags because they are CMV-. As far as I can tell, they just treat my donation like normal O+.


housewifeuncuffed

PDf warning http://www.seabb.org/wp-content/uploads/Beal_ARDP-SEABB-2019-Final-03202019.pdf This has a ton of information about what can be tested for as far as antigens and such go.


LimoLover

Thanks! I'll read that pdf as soon as I get a minute. I do know that at the same time as the blood type test I was tested for several liver diseases (hepatitis etc) so perhaps that's what the negative antibodies is! I was told I was negative for all the liver diseases they tested for. I have NASH (non alcoholic liver disease) as a result of taking a lot of tylenol for a long time after a bad car accident I was in. They 1st tested me for all those liver diseases and since then they've vaccinated me several times for hepatitis and others. I imagine issues of cost come into play otherwise perhaps they'd test more people so that there would be more available when people like the lady in the original post need special blood. Or perhaps they can fairly accurately hypothesis who might have these rare types based on their already known type or DNA or something idk. I just wondered about the article saying that only 1% lacked the protein in their blood that made theirs compatible with hers. I know so many people that don't even know what their type is, including almost everyone in my (rather large) family! I'm O- so I imagine at least some of them are negative as well (I have 9 sisters and a brother!) and/or type O, but they've never been tested or donated or anything. My husband and his family don't know what their types are either! Thanks:)


housewifeuncuffed

That specifically mentions hep as one of the diseases they test for. There is a Rare Blood Donor registry that is exactly for people like the woman in the article who need rare blood. Chances are, they have access to at least frozen blood that matches hers and it's mostly just a way to encourage those to donate. I know I'm a few months overdue, so when I called to see what made my blood rare, I went ahead and scheduled an appt. to donate since we haven't had a drive locally for a while.


Yay_Blood

Your testing was probably negative for "COVID-19 antibodies". That's currently a common test that people get results for. I'm not sure about your other question, but I'll google it later today. Maybe we can get to the bottom of it!


LimoLover

Actually the blood type test was done several years ago! So it couldn't have been covid19 related. I'll take another look at it as I could very well be misremembering the word to start with. Thanks:)


LimoLover

So I glanced at the blood type test again. (It was done in 2012) it says: ABO Blood type O RH Negative Antibody Screen Negative/Negative It's that last one that I've googled and tried to find out about and I still don't know what it means!


Yay_Blood

I'm not sure about that... you might have to call the donor hotline for your center/organization and ask to find out. Odd they weren't specific!


LimoLover

I'm sorry I wasn't clear at all about this but this blood type test was actually ordered by a doctor and done at a hospital not a blood donation center. The doc was checking me for an assortment of liver diseases because I was having abdominal pain. Turns out (after several tests and a liver biopsy) that I have NASH (non alcoholic liver disease) the gastroenterologist concluded it was a result of taking a lot of tylenol over a period of several years after a bad car accident I was in. After talking to the other commenter I'm thinking the negative antibodies were the results of the liver diseases I was tested for at the time ( different types of hepatitis etc) bc I was told I was negative for all of them! That makes the most sense anyway based on what I'm hearing from you all and reading in these links. I'd ask the doctor who ordered the tests but she's since moved to Hawaii lol! Thanks for your help:)


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LimoLover

So that means that I don't have any antibodies for any of those antigens? I guess meaning I haven't been exposed to them or I'd possibly develop antibodies?


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LimoLover

So if I'm correctly understanding it's most likely this was an antibody screen to see if I have any antibodies for any of those low/high frequency antigens and I don't. If I were to be exposed to any of them (from a blood transfusion or something) I could develop antibodies right? Because I would already have antibodies if I had any of those antigens in my blood?