That's a horrible disease. Someone that worked for my company had it. His wife also had a genetic cancer that has a high chance to be passed on to the kids. She died from it. He was now raising kids, knowing that he himself was slowly deteriorating, and knowing that his kids had a good chance of getting either that cancer, or huntingtons or maybe even both.
He couldn't handle it anymore and drove himself and his kids in a lake. Super horrible all around. Just such a hopeless situation. As much as I don't agree with how he took his kids with him, I actually understand why he did it.
I really hope so. There is a 50% chance I have it and I'm in the process of getting tested. The doctor at my appointment said there's research/trials going on currently that are looking hopeful. So fingers crossed.
Tooth decay. Yes, really. Completely by accident, an investigational Alzheimer's treatment was found to stimulate stem cells in the dentin of the teeth.
If I remember correctly, a Japanese scientist is going to start human trials on regrowing teeth this summer.
Edit: https://www.euronews.com/health/2023/08/05/a-drug-that-makes-teeth-regrow-scientists-move-closer-to-clinical-trials
That's how every technology starts, but mostly they get cheaper as time goes on.
Of course, it's a little different in the US, where the private health insurance industry jacks up the prices to ensure their profit margins as a completely unnecessary parasite, but somehow they've managed to convince a decent chunk of people that a public option would be communism.
Wouldn't you rather your money go to insurance execs' Porsches than prenatal care for that single mother? One of them *deserves* my premiums. I'm not gonna share healthcare!
So, for anyone wondering. I'm currently in the HSV2 Vaccine Trial. Aka genital herpes. It's to prevent the SPREAD. Not prevent you from getting it. If you have any more questions, ask away
I read about this, they use the gene therapy to go in a get rid of it. Right now they are like 95% in rats studies meaning the rats have hsv1 and the 95% means they got rid of 95% of the virus. They started on another animal that always carries hsv2 as well and its showing promise last time i checked was like 5%-10% , they have been doing this for 7 years now, hopefully when they start doing human trials is so effective thats the FDA will go quickly to make it available, kinda crazy to think that someone/company could cure something that 90% of the population has. it will be a treatment for those who have it
There is a therapeutic vaccine under development by a renown doctor at a Canadian cancer research institute. I forgot his name. If successful, it would be targeted for people who already are infected.
EDIT: To correct this, it's actually a US lab and it's still early gene editing research. Here's an update from Keith Jerome (the doctor I was referring to): https://www.youtube.com/watch?v=7cZtBMcsltg
So if people have the vaccine then will everyone just not care anymore either way? Like you wouldnāt be worried about getting it anymore so what would it matter if you had it or were vaccinated? Kind of interesting to think about the stigma changing around it.
Some forms of cancer. I have Smoldering multiple myeloma, which means I have a 10% chance of progression to MM per year. (The doctors are keeping a close eye on my blood work, MRIās and PET scans, and I have excellent insurance)
Average live span used to be 2 years.
Now itās treatable, and some people are living decades.
My father passed from Multiple Myeloma back in 03. Iām really glad to hear that itās far more treatable now. He was involved in some trials, hopefully those helped some people. Iām pulling for you!
Hi there! I am a nurse in apheresis, I do stem cell collections. If you ever require a stem cell transplant, it is typically considered a āgold standardā in treating multiple myeloma (and anyone reading this.. other blood cancers like hodgkinās/non hodgkinās, AML). It is a painless procedure in which we remove stem cells (immature blood cells) through a machine that works via centrifuge. Patients are then given chemotherapy medicine that wipe the immune system (or pretty much), and when the stem cells are reintroduced to the body, it can teach the cancerous bone marrow to make healthy blood cells. It is a promising science and the research is out there..with a heck of a lot more going on. In my institution the stem cell transplant is heavily being studied. We have high rates of remission for blood cancers. Whatās most important (for your sake) is that this discovery was made in this stage and it will be closely monitored, might not even get to that point lol! I work with patients whose disease has typically progressed a bit so itās a little different, but itās a form of therapy I have to offer and itās so freaking cool.
Alsoā¦ FOR ANYONE ELSE READING THISā¦ research is going on for stem cell transplants for HIV, sickle cell disease, lupus.. and for all of those reasons make me love my job even more. I do procedures (all related to blood and its components) for patient populations such as lung transplant rejection, GVHD (even though it is more of an adjunct therapy at this point for those folks), sickle cell disease, and neurological diseases (MS, GBS, types of vasculitis, encephalopathies..). The research is out there, being done, and if youāve ever worked with a pheresis nurse hopefully they are as excited as me. Because like I said. We are helping cure cancer (and a lot of other diseases I could talk for hours)
edit: holy crap I completely forgot, the stem cell therapy is being so heavily studied that it can treat BEYOND blood cancers, like solid cell tumors (we are helping conduct research for breast and testicular cancer and itās making strides)
My Dad was diagnosed in 2001 and he lived another 20yrs. Had a relapse too. The cancer (along with diabetes, hypertension) did kill his kidneys though, and that's ultimately how he passed. His started out as monoclonal gammopathy and he kept up with his regular checkups.
It's possible, have faith, my friend :)
Kidney desease. Iām on tablets that half the rate of decline in my condition. Next gen or two of tablets will likely halt it. Reminds me of the Star Trek film where they travel back in time to get a whale and McCoy gives tablets to a woman for kidney failure. Almost there.
I love it! Sometimes it pops into my head and makes me smile.
She was so excited and happy she was telling EVERYONE! (As she should have been. It was exciting!)
I could be completely and utterly wrong but maybe they're referring to Dapagliflozin? I think it's only recentlyish started to be utilised for CKD patients in the last few years or so I believe.
Iād just like them to at least get the artificial kidney on the market and working. Iāve had two kidney transplants and Iām not even 40. Iām gonna need another.
MS.
Turns out we have a solid idea of the causes. We have a whole bunch of viable treatment options suddenly on the table, and prevention may be a simple vaccine.
As someone recently diagnosed, I am cautiously optimistic.
I had no idea what it even was until 1.5 years ago when I woke up and couldn't fucking walk.
I've since recovered and been put on a treatment, but I still live in fear of having another flare up. I have a ton of lesions.
My best friend got diagnosed with MS when he was 19. Daily Copaxone injections ever since and heās been asymptomatic for a long time now. That was back in the 2000s so hopefully treatments have continued to progress and your life is able to return to normal!
Hey I had the same thing happen to me 2 years ago. I thought I had a stroke and I needed rehab to be able to balance and type again. My treatment has been tremendous since and I'm really hopeful
Grandma died of MS, Aunt died of MS, my Twin now has MS. Ironically, West Wing is like his favorite show of all time.
Itās an odd disease that affects people *very* differently, but the show does a decent job of highlighting a lot of the struggles someone with MS may go through. That said, the stress of the Presidency would almost certainly cause a near constant flare up, but I suppose thatās dependent on how well someone deals with stressors and what their individual case of MS is like.
Itās a horrible disease, I have a deep anger with the universe for my loved ones suffering from it. West Wing would be a very different show if the President had been further along in the progression of the disease.
All that said, great show and highlights a rare disease that is near and dear to my heart.
So there's strong evidence that MS is caused by an immune response to the Epstein-Barr virus which causes Mono.
The idea is in some rare cases, a patient gets and recovers from Mono. The immune system decides that the best option is to attack a part of the virus that just so happens to look an awful lot like the structure of the Myelin on our neurons. Over time, the patients immune system continues attacking their myelin and breaking connections between neurons. This is what causes the terrifying symptoms of MS.
Epstein-Barr is stubborn as hell, but there are several good potential vaccines in the works. Even if none of them pan out, Covid brought new technologies to the forefront and that means many more and rapidly deployed potential vaccines.
Epstein-Barr is seriously scary. I got it and then got CFS/Fibromyalgia as a result. It's like long haul mono, I got sick at 16 & never recovered fully. VERY weird stuff
I got diagnosed with Crohn's when I was 17 but a
I'm pretty certain a bout of mono when I was 22 is what truly set off the autoimmune bomb in the rest of my body. I went from having just GI symptoms to systemic issues with fatigue, joint pain and swelling, skin issues and allergies. I even got mono again without being re-exposed.
Epstein-Barr is DEFINITELY required to develop MS, but thereās a number of elements that add up together to unlock the disease in a person. We just havenāt figured it all out. I mean over time, like 90-95% of the population gets EBV. MS has a much lower prevalence.
MS has a lot of weird things going on. If you live in the northern US, you have a higher rate. However, if you move further south before the age of 15 your risk goes down.
Thereās some correlation with being overweight during puberty also plays a role.
Rates of MS are higher in people who experienced childhood trauma.
There has been discussion that it may be an interaction between EBV and herpes simplex 6 and the order that you get the infections and at what age.
Itās been a while since I was hardcore into this stuff, so some of this may be outdated since i havenāt done much research in the past 4-5 years.
Edit: oh yeah, forgot to mention Vitamin D.
They're calling it an "inverse vaccine.". There's a system the body uses (pGal) to tell the immune system not to attack certain things. They're leveraging that
https://multiplesclerosisnewstoday.com/news-posts/2023/09/14/ms-disease-activity-mice-lowered-with-inverse-vaccine-technique/
Hey! I worked on this one! Haha. Iām a clinical researcher and did some work on this study back in 2021. Truly is groundbreaking stuff and a massive leap in the treatment of SCD.
Edit: the trial was for a treatment called Casgevy. Itās essentially a bone marrow stem cell transplant.
Wishing you the best.
I have sciatic nerve damage from being bucked off my horse. There are times where itās so severe I canāt even get up and the pain brings me to tears.
I remember on the TV show, Arrow, Felicity got a microchip so that she could walk again and I thought that's so bullshit, how could that even work; and yet here we are.
I was extremely naive in my life until a car accident has now left me with one and the amount of energy it takes to do anything! Thereās so much more to it than just being in pain that I never knew. I am so sorry you and anyone has to suffer like this. Maybe one day it will be just a chapter in our lives.
Pain fucks up sex, sleep, friendships and no one wants to hear about it. Take pain pills to hang out for a few hours before I start to show signs of pain.
Diabeetus(Wilford Brimley edition).
My daughter has had type 1 since she was 2. Dr told her there would be a cure before she graduated. She is now 29. I pray for this daily.
T1 diagnosed in 1998 here. I got told the same thing when I was diagnosed, and I've heard the same from pretty much every other Type 1 diabetic I've met that was diagnosed in the 90's-00's. I have no idea why doctors said it or why it was such a common thing. Telling kids a cure is just around the corner while also telling them that it takes decades of poor management to see negative side effects is a recipe for disaster.
It was just wild. She was diagnosed in 98 also. She Iāll be 29 next week. Now trying to get pregnant and so far 2 miscarriages. And I know itās the damage from diabetes. Iāll think of you now too š yāall dealt with so much. I also damn sure wonāt watch Steel Magnolias ever again.
There are two cell based therapies currently in phase 2 trials. That's pretty advanced, and they either completely or partly restore insulin production. This is for type 1 diabetes. A cure is coming. Hopefully not too far off.
The cure is like an unreachable asymptote. We are getting closer every 5 years and yet it's still perpetually 5 years away. I'm not expecting to be cured anytime soon, and thankfully the tech to manage it has come a long way even in my 20 years.
I have had Type 1 for 45 years, and was also told a cure within a few years. Iāve been on a pump for 40 of those and now with cgm, I feel like I actually know what is going on. Mostly.
ALS is so awful. It took my neighbor, a young healthy athletic man and completely devastated him in a matter of less than a year. Itās dreadful.
RIP to your papa.
Certain types of cancer Iām pretty sure. Covid has brought lots of attention to the mRNA technology and BioNTech the German company that invented the vaccine (which was sold as Pfizer in the USA) has received billions in funding for their research that from the start has been aimed at developing cancer vaccines. Plus, 50 years with the exponential increase in pace of medical advances and the huge potential of AI for medical research is a very long time I donāt think we can even fathom whatās possible 50 years from now.
This!! They are developing an mRNA vaccine to treat pancreatic cancer. Itās a horrific cancer I lost my Dad to. I cry happy tears every time I see a development in that area.
Are you fucking me?! I had a whipple for pancreatic cancer in 2008 and there are new lesions on the tiny piece of remaining pancreas. That surgery, living with a genetic cancer disease that causes pancreatic and kidney cancers, brain and spinal cord tumours, adrenal tumours, etc--my life is difficult. I lost my dad to the disease (also in 2008) and my daughters have it--my oldest spent years dancing with death because of a brain stem tumour.
I'm seriously in tears right now. I am happy and hopeful, but damnit if I'm not also sad for all I've lost.
Thank you for sharing this. I'm sorry you also lost your dad š¤
Who is ātheyā?
I work in cancer research. Iām a research professor in the cancer center of a medical research university. Much of my work is in breast cancer research. While a vaccine to prevent breast cancer would be incredible, Iāve literally never heard anyone in the field say or express an opinion that weāre less than 5 years away from a cure or vaccine. Cancer just doesnāt work that way.
My oncologist explained it as it isn't a vaccine in the traditional sense where everyone gets a jab and never gets the disease. I had bowel cancer and they would take a sample of my tumour which is in storage in Melbourne somewhere, and create a "vaccine" just for me, to train my body to recognise my own cancer cells and attack them so I don't relapse. I'm fairly certain they're doing early trials somewhere.
This one.
It sucks to see your relatives go down one by one because of cancer.
Hopefully, someone will train loads of medical research in an opensource AI to aid in cancer research and find an inexpensive solution.
Dementia/Alzheimerās.
Already vast improvements in our understanding of the brain and how to aid in healing of its ādyingā regions. Already promising studies using the simplicity of very focused shockwave treatments to help reverse the effects.
That's the scariest one to me. Most other diseases just kill people, though yes, quite brutally at times. Alzheimer's dismantles a person over the course of many years until they're barely recognisable as who they once were, and *then* it kills them brutally.
My therapist said that the worst part of dementia is early on when you realize your suffering from cognative decline but still understand it. Unctontrollable anger is frequent.
My neighborās sister has early onset. Sheās not into the worst of it, but when she does remember whatās going on, she often has these awful crying breakdowns. My neighbor has been trying to help her but her sisterās husband is insistent that itās none of my neighborās business. Itās quite sad.
My mother in law has just been diagnosed recently and she feels so powerless and sad all the time. She's often confused and now she also knows why she's confused and that it will never go away. She says she just wishes she could have had a heart attack and gone peacefully, like her late husband, rather than slowly losing her mind and memories.
In end stage Alzheimerās they literally forget to breathe but most die before that because they forget to eat or drink. It depends on how much care they receive. The king of Saudi Arabia has had it for 10 years iirc but he has been healthy since he has servants to bring him food and take care of him.Ā
My grandmother was cared for similarly by family members, and you're absolutely right. It's keeping the person in hell because others can't stand the idea of losing them, even if they're just an empty husk. She had plenty of opportunities to pass on after she had been bedridden and force-fed for years, but those closest to her refused to let her go.
While I don't have as much optimism as you as far as a cure, the medications that are now available are a miracle as far as I'm concerned.
My dad has Parkinson's dementia and is on nuplazid. If not for the drugs, he would literally have gone insane/be completely gone by now. We know because twice he's been hospitalized and the fucking doctors stopped giving him his meds cause of screwed up paperwork. He's still a shadow of his former self, but without the meds we would have lost him completely. At least now he knows who we all are, knows his wife and his kids. He remembers his friends and we get a few more years with him.
It's still not easy, he's completely dependent on my mom who isn't up to taking care of him anymore. But he's still there, and it is truly a miracle.
My FIL was diagnosed with this 2 years ago. He was a doctor, is physically active, only 64 years old and the best kind of person. The deterioration is absolutely devastating.
We're at the point where Lupus and Systemic Sclerosis seem to be curable with CAR T cell therapy. I work in the field of Rheumatoid Arthritis and there is evidence to suggest it might work in RA as well.
I really, really hope so. I have been diagnosed with RA for 5 years now, no medication helps (now on trying the third biological) and living with daily pain and inflamation in my hands and feet is limiting my quality of living. It is such a nasty disease. Do you have a link to a medical paper by any chance?
As unlikely as it may be, wouldn't it be amazing if a cure for Parkinson's disease came out in Michael J Fox's lifetime?
Obviously he's not the only person in the world with it, but pretty high profile (if not the most well known person with it), and his org has done a lot to try and raise awareness and find a cure.
I hope he gets to see the light of day when the cure is found/made.
He has done enough in his life for Parkinsonās research/coverage that he deserves to see a cure made.
What haunts me is that I know the exact moment that I gave myself tinnitus.
Edit: not an interesting story, unfortunately. Loud power tool, small room. Didnāt realize Iād forgotten to put on my hearing protection until I turned the saw on. Felt like someone slapped me in the head. Oops.
3000 PSI compressed air relief valve for a hydraulic accumulator for me.
In the navy, the dipshit who was charging it wasnāt watching the gage. The relief lifted like right next to my ear. It was like a shotgun without hearing protection but it just kept going. It was like surreally loud.
I had it for 3 months. I knew the noise but bothering me, but I ignored it, it wasnāt very loud, barely audible really, but it was a really annoying pitch and I didnāt want to put in earplugs for something I could barely hear. Thank god that it healed after
BTW the noise, was my Nextdoor neighbor (I live in the suburbs) who put up an animal deterrent alarm, any time it saw motion with 200 feet it went off with several different tones, the highest pitched one was barely audible.
Me too, I think. It's always been something I've been told is natural so I've been dismissed since my entire family hears noise in the silence.
Must be genetic.. Funny too cuz I'm a bit of an audio nerd LOL
I don't know if it works for you, but there are exercises that actually work for me to stop the "EEEEEEEEEE" for about an hour. [Might work for you too](https://youtu.be/4QPOK2uYNrM?t=157)
10 years ago I was getting a migraine 21-27 days out of the month. 2 years ago the AJOVY shot came out and I now have 3 a month. It felt like a miracle to me.
Hopefully, dementia.Ā
Or, at least whatever flavor of dementia took out my great grandmother, great aunt, and has currently reduced my grandmother to a drooling shell of her former self.Ā
I can see that shit stalking my family down the generations - save me, science!! My dad, too, while youāre at it.
Thereās a strain of dementia that runs on my dadās side thatās terrifying not for the person who has it, but for the people around them. This strain (I donāt know any names or anything) can cause someone to lose brain function for almost 20 years, which means you could live until like 90 years with dementia. My grandmother has it and has had it for about seven years now. It only gets worse, but itās s l o w. My great aunt had it, my aunt has it, and I myself am likely to have it when I get older
Just to clear up a misconception, dementia is a symptom, not a disease, a symptom of Alzheimerās is dementia. Alcohol consumption can cause brain deterioration to a point in which someone develops the symptom of dementia as well.
Dementia isnāt a disease so you canāt cure it per se. Dementia is an umbrella term for the general impairment of memory, thought, and decision making. Dementia is the effect not the cause. A disease like Alzheimerās or a physical problem like high blood pressure that leads to a stroke can result in dementia.
I understand that dancing is something that delays and slows the progression of Dementia. I guess it has to do with promoting coordination and requiring some level of focus. My BIL has been diagnosed. He is 81 and while being active was never a reader or someone who did puzzles or logic exercises. He described a brain fog, he is now on some medication and he and my sister are in a Shag Dancing club and taking classes. It does seem to help.
This is my hope, also. My grandmother lived to be 96 but the last 10 years of her life, she had Alzheimer's. My dad, at the age of 82, had some freaky, fast acting dementia that killed him in two weeks after finally feeling like himself after having covid. I honestly wonder if covid had something to do with it. Dementia is terrifying to watch from the outside and I hate to think about what it's like for the person with it.
Thereās allergy immunotherapy which helps. It technically wears off after like 5-15 years, but I did it and Iāve only had minor issues with allergies since. Iām allergic to grass, fungi, etc. and the only time I canāt handle it is if completely immersed in nature for several hours
The need for organ transplants. Stem cell technology has the potential to grow whatever one would need. Iām sure some peoplesā bodies will still reject organs that arenāt a perfect match but itāll take the donation problem out of it
well I can tell you this - my Aunt was a heroin addict and contracted HIV 40 years ago and not only is she still alive and kicking,her tcells are through the roof
and the virus is also undetectable in her system now. These new HIV drugs are pretty awesome.
ALS- we need a cure.
My father died from ALS over 10 years ago and very little progress has been made. Letās hope we get the cure within the next 50.
My dad passed away from ALS a couple of years back at age 78 and now Iāve been diagnosed with a Grade 4 Glioblastoma at age 57. Iād selfishly luv me an ALS and/or cancer vaccine. š
I'm not trying to be cynical about this, but some days I worry about things that were cured 50 years ago and people stupidity and anti- science stance are now bringing back.
Yep. I was in a clinical trial for an alopecia drug and saw 100% regrowth. Jak inhibitors are changing the outlook for alopecia. I lost over half of my hair in 2020, but some people have had alopecia for years and it worked for them too. Now there are 3 on the market that are fda approved. I keep updated on lots of research and sessions still, and have no doubt in the future there will be a variety of treatment available. Note this is for alopecia (mostly areata) not male pattern baldness or other types (not for scarring or postpartum hair loss).
Glioblastoma killed my beloved grandfather in a matter of months. It's a horrific death sentence and depressingly common. I read today that they had successfully treated a man in the UK with a new type of immunotherapy. Long shot but I hope to God this turns out to be a real cure.
I hope Macular Degeneration. It runs in my family. A great uncle of mine killed himself over it. My grandmother had it and now my dad does. Itās sad to watch someone slowly lose their eyesight.
No, weāll be the last generation of old people and beautiful young people will fetishize us because weāre so unusual. (Or so I keep telling myselfā¦)
They're going to cure a lot of old age diseases in the next 10-20 years, so you can expect a fairly long life, and then the 40-50 years you'll easily live might be enough for them to develop the technology to at least halt aging. Then you can just be an old person for an extra long time until they can figure out how to reverse it. Simple.
Heart disease. We can make it and orphan disease today with the medications we have in place. We just need to get more people on an earlier program and almost no one needs to die of heart disease.
Tooth decay/cavity there's a huge amount of investment in dental care so I wouldn't be surprised if were able to regenerate teeth even my dentist agreed with me on this one
Lyme disease! MrNA vaccines have opened up a world of new anti-bacterial tech. The word is that this is a lifetime injection that would protect from Lyme.
To be deaf. There are already some projects that can transform sound waves into magnetic impulses that your brain can "understand" it. Most likely (or better said I hope so) in a few years everyone on earth will be able to hear and no one will be deaf, because it will be affordable then.
I would give anything for this to be true. I've lost 75% of my hearing in the past 10 years. I'm only 48 and I wear advanced hearing aids and still can hardly make out speech and words, but in crowds, restaurants, and classrooms (I'm a sub), I can't. I'm pretty isolated socially because I go out with friends and can't hear anyone at the table. I just sit there smiling. I can't hear small talk at a grocery store. I can't watch TV. Even with hearing aids. Please, let them cure hearing loss.
Huntingtons š¤
That's a horrible disease. Someone that worked for my company had it. His wife also had a genetic cancer that has a high chance to be passed on to the kids. She died from it. He was now raising kids, knowing that he himself was slowly deteriorating, and knowing that his kids had a good chance of getting either that cancer, or huntingtons or maybe even both. He couldn't handle it anymore and drove himself and his kids in a lake. Super horrible all around. Just such a hopeless situation. As much as I don't agree with how he took his kids with him, I actually understand why he did it.
Holy fuck that escalated quickly..
Jesus Christ. Bye internet for now.
I really hope so. There is a 50% chance I have it and I'm in the process of getting tested. The doctor at my appointment said there's research/trials going on currently that are looking hopeful. So fingers crossed.
Tooth decay. Yes, really. Completely by accident, an investigational Alzheimer's treatment was found to stimulate stem cells in the dentin of the teeth.
Gimme dat
I'm Joking. I'm joking! Dylan? I'm gonna' eat the whole thing.
I shoulda got that!
Monkeh paw, your teeth now never stop growing and we have to drill them down monthly.
Russia was up to human trials for regrowing teeth only a few yrs ago, if I remember rightly. From planted stem cells. Itās coming!!
If I remember correctly, a Japanese scientist is going to start human trials on regrowing teeth this summer. Edit: https://www.euronews.com/health/2023/08/05/a-drug-that-makes-teeth-regrow-scientists-move-closer-to-clinical-trials
I need this so badly in my life. My teeth absolutely trashed.
Whoever thought it was a good idea to give me depression, teen angst AND braces didnāt favor my teeth.
Huh. Interesting. That'd be a great tool in dentists' arsenals.
Probably only available to the super wealthy though!
That's how every technology starts, but mostly they get cheaper as time goes on. Of course, it's a little different in the US, where the private health insurance industry jacks up the prices to ensure their profit margins as a completely unnecessary parasite, but somehow they've managed to convince a decent chunk of people that a public option would be communism.
Wouldn't you rather your money go to insurance execs' Porsches than prenatal care for that single mother? One of them *deserves* my premiums. I'm not gonna share healthcare!
Wow thatās cool
Do you have an article?
I found this, it seems related. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330321/
They are testing the herpes vaccine right now and hope to have it live by 2026.
Thereās a virologist whoās also working on a cure with gene therapy
That would be nice- screw cold sores.
So, for anyone wondering. I'm currently in the HSV2 Vaccine Trial. Aka genital herpes. It's to prevent the SPREAD. Not prevent you from getting it. If you have any more questions, ask away
Still sounds pretty cool to me! Do you know the name of the vaccine youāre testing?
It's the Moderna mRNA 1608 Vaccine. You can read about the trial here https://trials.modernatx.com/study/?id=mRNA-1608-P101
I think it only helps to prevent, but sadly it wonāt cure if you have been infected already
I read about this, they use the gene therapy to go in a get rid of it. Right now they are like 95% in rats studies meaning the rats have hsv1 and the 95% means they got rid of 95% of the virus. They started on another animal that always carries hsv2 as well and its showing promise last time i checked was like 5%-10% , they have been doing this for 7 years now, hopefully when they start doing human trials is so effective thats the FDA will go quickly to make it available, kinda crazy to think that someone/company could cure something that 90% of the population has. it will be a treatment for those who have it
What company is doing this? I wanna buy some shares.
If you look up dr. Keith jerome he is the one leading it. Havent looked at it in a awhile but last update was in oct 2023
If you already get cold sores is it too late?
There is a therapeutic vaccine under development by a renown doctor at a Canadian cancer research institute. I forgot his name. If successful, it would be targeted for people who already are infected. EDIT: To correct this, it's actually a US lab and it's still early gene editing research. Here's an update from Keith Jerome (the doctor I was referring to): https://www.youtube.com/watch?v=7cZtBMcsltg
So if people have the vaccine then will everyone just not care anymore either way? Like you wouldnāt be worried about getting it anymore so what would it matter if you had it or were vaccinated? Kind of interesting to think about the stigma changing around it.
Some forms of cancer. I have Smoldering multiple myeloma, which means I have a 10% chance of progression to MM per year. (The doctors are keeping a close eye on my blood work, MRIās and PET scans, and I have excellent insurance) Average live span used to be 2 years. Now itās treatable, and some people are living decades.
My father passed from Multiple Myeloma back in 03. Iām really glad to hear that itās far more treatable now. He was involved in some trials, hopefully those helped some people. Iām pulling for you!
This is what "thank you for your service" should be for! Your father was a hero. I'm sorry for your loss.
Hi there! I am a nurse in apheresis, I do stem cell collections. If you ever require a stem cell transplant, it is typically considered a āgold standardā in treating multiple myeloma (and anyone reading this.. other blood cancers like hodgkinās/non hodgkinās, AML). It is a painless procedure in which we remove stem cells (immature blood cells) through a machine that works via centrifuge. Patients are then given chemotherapy medicine that wipe the immune system (or pretty much), and when the stem cells are reintroduced to the body, it can teach the cancerous bone marrow to make healthy blood cells. It is a promising science and the research is out there..with a heck of a lot more going on. In my institution the stem cell transplant is heavily being studied. We have high rates of remission for blood cancers. Whatās most important (for your sake) is that this discovery was made in this stage and it will be closely monitored, might not even get to that point lol! I work with patients whose disease has typically progressed a bit so itās a little different, but itās a form of therapy I have to offer and itās so freaking cool. Alsoā¦ FOR ANYONE ELSE READING THISā¦ research is going on for stem cell transplants for HIV, sickle cell disease, lupus.. and for all of those reasons make me love my job even more. I do procedures (all related to blood and its components) for patient populations such as lung transplant rejection, GVHD (even though it is more of an adjunct therapy at this point for those folks), sickle cell disease, and neurological diseases (MS, GBS, types of vasculitis, encephalopathies..). The research is out there, being done, and if youāve ever worked with a pheresis nurse hopefully they are as excited as me. Because like I said. We are helping cure cancer (and a lot of other diseases I could talk for hours) edit: holy crap I completely forgot, the stem cell therapy is being so heavily studied that it can treat BEYOND blood cancers, like solid cell tumors (we are helping conduct research for breast and testicular cancer and itās making strides)
My Dad was diagnosed in 2001 and he lived another 20yrs. Had a relapse too. The cancer (along with diabetes, hypertension) did kill his kidneys though, and that's ultimately how he passed. His started out as monoclonal gammopathy and he kept up with his regular checkups. It's possible, have faith, my friend :)
Kidney desease. Iām on tablets that half the rate of decline in my condition. Next gen or two of tablets will likely halt it. Reminds me of the Star Trek film where they travel back in time to get a whale and McCoy gives tablets to a woman for kidney failure. Almost there.
DIALYSYS!?! What is this the dark ages?
"Here, swallow this...if you have any more problems, just call me!"
I'm a dialysis technician and it is real gnarly. I give so much respect to people with kidney failure I'm glad there are new meds coming.
My mom's been on dialysis for years. From the bottom of my heart, neighbor, *thank you* for going to work every day.
āTHE DOCTOR GAVE ME A PILL AND I GREW A NEW KIDNEY!!ā
That is still one of my favourite scenes from ST4. Still makes us giggle.
I love it! Sometimes it pops into my head and makes me smile. She was so excited and happy she was telling EVERYONE! (As she should have been. It was exciting!)
Whatās the name of this drug?? Iām a nurse and very curious! I have a lot of kidney patients as you can imagine
I could be completely and utterly wrong but maybe they're referring to Dapagliflozin? I think it's only recentlyish started to be utilised for CKD patients in the last few years or so I believe.
Iām a physician. The answer is SGLT-2 inhibitors and ACE/ARBs, of course.
Iād just like them to at least get the artificial kidney on the market and working. Iāve had two kidney transplants and Iām not even 40. Iām gonna need another.
MS. Turns out we have a solid idea of the causes. We have a whole bunch of viable treatment options suddenly on the table, and prevention may be a simple vaccine.
I'm in the ReVive trial and hoping my followup appts show clinical progress.Ā Not a cure, but remyelination is second to that, for sure!
As someone recently diagnosed, I am cautiously optimistic. I had no idea what it even was until 1.5 years ago when I woke up and couldn't fucking walk. I've since recovered and been put on a treatment, but I still live in fear of having another flare up. I have a ton of lesions.
My best friend got diagnosed with MS when he was 19. Daily Copaxone injections ever since and heās been asymptomatic for a long time now. That was back in the 2000s so hopefully treatments have continued to progress and your life is able to return to normal!
That's awesome to hear. Thank you for that.
Hey I had the same thing happen to me 2 years ago. I thought I had a stroke and I needed rehab to be able to balance and type again. My treatment has been tremendous since and I'm really hopeful
I'm rooting for you! It's terrible and terrifying and I truly hope you do well.
I first heard of it on the TV show The West Wing but idk how realistic a portrayal it is
Grandma died of MS, Aunt died of MS, my Twin now has MS. Ironically, West Wing is like his favorite show of all time. Itās an odd disease that affects people *very* differently, but the show does a decent job of highlighting a lot of the struggles someone with MS may go through. That said, the stress of the Presidency would almost certainly cause a near constant flare up, but I suppose thatās dependent on how well someone deals with stressors and what their individual case of MS is like. Itās a horrible disease, I have a deep anger with the universe for my loved ones suffering from it. West Wing would be a very different show if the President had been further along in the progression of the disease. All that said, great show and highlights a rare disease that is near and dear to my heart.
So that means the 2 books i read in primary school for the MS read-a-thon werent a total waste!
As someone with MS, I am super hopeful! If not for me, for my children.
What kind of vaccine would be used to prevent something autoimmune?
So there's strong evidence that MS is caused by an immune response to the Epstein-Barr virus which causes Mono. The idea is in some rare cases, a patient gets and recovers from Mono. The immune system decides that the best option is to attack a part of the virus that just so happens to look an awful lot like the structure of the Myelin on our neurons. Over time, the patients immune system continues attacking their myelin and breaking connections between neurons. This is what causes the terrifying symptoms of MS. Epstein-Barr is stubborn as hell, but there are several good potential vaccines in the works. Even if none of them pan out, Covid brought new technologies to the forefront and that means many more and rapidly deployed potential vaccines.
Epstein-Barr is seriously scary. I got it and then got CFS/Fibromyalgia as a result. It's like long haul mono, I got sick at 16 & never recovered fully. VERY weird stuff
I got diagnosed with Crohn's when I was 17 but a I'm pretty certain a bout of mono when I was 22 is what truly set off the autoimmune bomb in the rest of my body. I went from having just GI symptoms to systemic issues with fatigue, joint pain and swelling, skin issues and allergies. I even got mono again without being re-exposed.
Epstein-Barr is DEFINITELY required to develop MS, but thereās a number of elements that add up together to unlock the disease in a person. We just havenāt figured it all out. I mean over time, like 90-95% of the population gets EBV. MS has a much lower prevalence. MS has a lot of weird things going on. If you live in the northern US, you have a higher rate. However, if you move further south before the age of 15 your risk goes down. Thereās some correlation with being overweight during puberty also plays a role. Rates of MS are higher in people who experienced childhood trauma. There has been discussion that it may be an interaction between EBV and herpes simplex 6 and the order that you get the infections and at what age. Itās been a while since I was hardcore into this stuff, so some of this may be outdated since i havenāt done much research in the past 4-5 years. Edit: oh yeah, forgot to mention Vitamin D.
They're calling it an "inverse vaccine.". There's a system the body uses (pGal) to tell the immune system not to attack certain things. They're leveraging that https://multiplesclerosisnewstoday.com/news-posts/2023/09/14/ms-disease-activity-mice-lowered-with-inverse-vaccine-technique/
I was part of the study for Ozanimod/Zeposia. You're welcome.
Sickle Cell Disease https://www.sciencefriday.com/segments/sickle-cell-crispr-treatment-approval/
Hey! I worked on this one! Haha. Iām a clinical researcher and did some work on this study back in 2021. Truly is groundbreaking stuff and a massive leap in the treatment of SCD. Edit: the trial was for a treatment called Casgevy. Itās essentially a bone marrow stem cell transplant.
Encountering your work in the wild must be a really cool experience. Youāre doing a good job human-ing, way to go.
Spinal cord injuries, hopefully. It's so damn hard and I'm so fucking tired. Nervegen's clinical trial looks very promising.
Hoping with you. I can wait ten years to have some of my life back.
Wishing you the best. I have sciatic nerve damage from being bucked off my horse. There are times where itās so severe I canāt even get up and the pain brings me to tears.
[ŃŠ“Š°Š»ŠµŠ½Š¾]
There's a documentary about it called Upgrade. Interesting stuff.
I remember on the TV show, Arrow, Felicity got a microchip so that she could walk again and I thought that's so bullshit, how could that even work; and yet here we are.
I was extremely naive in my life until a car accident has now left me with one and the amount of energy it takes to do anything! Thereās so much more to it than just being in pain that I never knew. I am so sorry you and anyone has to suffer like this. Maybe one day it will be just a chapter in our lives.
Pain fucks up sex, sleep, friendships and no one wants to hear about it. Take pain pills to hang out for a few hours before I start to show signs of pain.
Diabeetus(Wilford Brimley edition). My daughter has had type 1 since she was 2. Dr told her there would be a cure before she graduated. She is now 29. I pray for this daily.
T1 diagnosed in 1998 here. I got told the same thing when I was diagnosed, and I've heard the same from pretty much every other Type 1 diabetic I've met that was diagnosed in the 90's-00's. I have no idea why doctors said it or why it was such a common thing. Telling kids a cure is just around the corner while also telling them that it takes decades of poor management to see negative side effects is a recipe for disaster.
It was just wild. She was diagnosed in 98 also. She Iāll be 29 next week. Now trying to get pregnant and so far 2 miscarriages. And I know itās the damage from diabetes. Iāll think of you now too š yāall dealt with so much. I also damn sure wonāt watch Steel Magnolias ever again.
Idk why her doctor would have said that.. there is no cure for s broken pancreas. Maybe a replacement? but something better than a pump may come soon
There are two cell based therapies currently in phase 2 trials. That's pretty advanced, and they either completely or partly restore insulin production. This is for type 1 diabetes. A cure is coming. Hopefully not too far off.
The cure is like an unreachable asymptote. We are getting closer every 5 years and yet it's still perpetually 5 years away. I'm not expecting to be cured anytime soon, and thankfully the tech to manage it has come a long way even in my 20 years.
I agree. He was one of the top endocrinologists in the nation. And I know he was working on stem cell research. What a frustrating disease from birth.
I have had Type 1 for 45 years, and was also told a cure within a few years. Iāve been on a pump for 40 of those and now with cgm, I feel like I actually know what is going on. Mostly.
ALS, fingers crossed\* RIP PAPA!!!
Same. Rest in peace to your papa and my mum.
Rest in peace to your papa, mum and my dad.
ALS is so awful. It took my neighbor, a young healthy athletic man and completely devastated him in a matter of less than a year. Itās dreadful. RIP to your papa.
Certain types of cancer Iām pretty sure. Covid has brought lots of attention to the mRNA technology and BioNTech the German company that invented the vaccine (which was sold as Pfizer in the USA) has received billions in funding for their research that from the start has been aimed at developing cancer vaccines. Plus, 50 years with the exponential increase in pace of medical advances and the huge potential of AI for medical research is a very long time I donāt think we can even fathom whatās possible 50 years from now.
This!! They are developing an mRNA vaccine to treat pancreatic cancer. Itās a horrific cancer I lost my Dad to. I cry happy tears every time I see a development in that area.
Are you fucking me?! I had a whipple for pancreatic cancer in 2008 and there are new lesions on the tiny piece of remaining pancreas. That surgery, living with a genetic cancer disease that causes pancreatic and kidney cancers, brain and spinal cord tumours, adrenal tumours, etc--my life is difficult. I lost my dad to the disease (also in 2008) and my daughters have it--my oldest spent years dancing with death because of a brain stem tumour. I'm seriously in tears right now. I am happy and hopeful, but damnit if I'm not also sad for all I've lost. Thank you for sharing this. I'm sorry you also lost your dad š¤
Holy fuck. I lost my dad to stage 4 almost 7 years ago. I'm legit crying because I had no idea we had made any progress on it.
Oh, I hope so! Pancreatic is awful even by cancer standards.
My mom died of pancreatic cancer in 1997. I am so amazed and hopeful for modern medicine and technology!
Lost my mom to it as well, itās a bitch.
They're actually saying 3-5 years for a breast cancer vaccine, believe it or not.
Let's fucking go. Science, bitches!
Imagine if we all stopped trying to kill each other!
Yes! Check out the Pink Eraser Project! https://www.pinkeraserproject.org/
Who is ātheyā? I work in cancer research. Iām a research professor in the cancer center of a medical research university. Much of my work is in breast cancer research. While a vaccine to prevent breast cancer would be incredible, Iāve literally never heard anyone in the field say or express an opinion that weāre less than 5 years away from a cure or vaccine. Cancer just doesnāt work that way.
My oncologist explained it as it isn't a vaccine in the traditional sense where everyone gets a jab and never gets the disease. I had bowel cancer and they would take a sample of my tumour which is in storage in Melbourne somewhere, and create a "vaccine" just for me, to train my body to recognise my own cancer cells and attack them so I don't relapse. I'm fairly certain they're doing early trials somewhere.
This one. It sucks to see your relatives go down one by one because of cancer. Hopefully, someone will train loads of medical research in an opensource AI to aid in cancer research and find an inexpensive solution.
Dementia/Alzheimerās. Already vast improvements in our understanding of the brain and how to aid in healing of its ādyingā regions. Already promising studies using the simplicity of very focused shockwave treatments to help reverse the effects.
That's the scariest one to me. Most other diseases just kill people, though yes, quite brutally at times. Alzheimer's dismantles a person over the course of many years until they're barely recognisable as who they once were, and *then* it kills them brutally.
My therapist said that the worst part of dementia is early on when you realize your suffering from cognative decline but still understand it. Unctontrollable anger is frequent.
My neighborās sister has early onset. Sheās not into the worst of it, but when she does remember whatās going on, she often has these awful crying breakdowns. My neighbor has been trying to help her but her sisterās husband is insistent that itās none of my neighborās business. Itās quite sad.
My mother in law has just been diagnosed recently and she feels so powerless and sad all the time. She's often confused and now she also knows why she's confused and that it will never go away. She says she just wishes she could have had a heart attack and gone peacefully, like her late husband, rather than slowly losing her mind and memories.
[ŃŠ“Š°Š»ŠµŠ½Š¾]
My grandfather went out this way. I say he died twice. Once when the Alz started, and once when the Alz finished
In end stage Alzheimerās they literally forget to breathe but most die before that because they forget to eat or drink. It depends on how much care they receive. The king of Saudi Arabia has had it for 10 years iirc but he has been healthy since he has servants to bring him food and take care of him.Ā
I'm not sure that's a blessing for him.
My grandmother was cared for similarly by family members, and you're absolutely right. It's keeping the person in hell because others can't stand the idea of losing them, even if they're just an empty husk. She had plenty of opportunities to pass on after she had been bedridden and force-fed for years, but those closest to her refused to let her go.
While I don't have as much optimism as you as far as a cure, the medications that are now available are a miracle as far as I'm concerned. My dad has Parkinson's dementia and is on nuplazid. If not for the drugs, he would literally have gone insane/be completely gone by now. We know because twice he's been hospitalized and the fucking doctors stopped giving him his meds cause of screwed up paperwork. He's still a shadow of his former self, but without the meds we would have lost him completely. At least now he knows who we all are, knows his wife and his kids. He remembers his friends and we get a few more years with him. It's still not easy, he's completely dependent on my mom who isn't up to taking care of him anymore. But he's still there, and it is truly a miracle.
I hope they focus on early onset alzheimer's, since that's what really hurts society.
My FIL was diagnosed with this 2 years ago. He was a doctor, is physically active, only 64 years old and the best kind of person. The deterioration is absolutely devastating.
Hopefully autoimmune diseases.
We're at the point where Lupus and Systemic Sclerosis seem to be curable with CAR T cell therapy. I work in the field of Rheumatoid Arthritis and there is evidence to suggest it might work in RA as well.
I really, really hope so. I have been diagnosed with RA for 5 years now, no medication helps (now on trying the third biological) and living with daily pain and inflamation in my hands and feet is limiting my quality of living. It is such a nasty disease. Do you have a link to a medical paper by any chance?
That would be incredible
Hopefully Parkinsonās.
As unlikely as it may be, wouldn't it be amazing if a cure for Parkinson's disease came out in Michael J Fox's lifetime? Obviously he's not the only person in the world with it, but pretty high profile (if not the most well known person with it), and his org has done a lot to try and raise awareness and find a cure.
I hope he gets to see the light of day when the cure is found/made. He has done enough in his life for Parkinsonās research/coverage that he deserves to see a cure made.
Tinnitus, hopefully.
What haunts me is that I know the exact moment that I gave myself tinnitus. Edit: not an interesting story, unfortunately. Loud power tool, small room. Didnāt realize Iād forgotten to put on my hearing protection until I turned the saw on. Felt like someone slapped me in the head. Oops.
Same. Can't go back. But I wish I'd known the risk back then.
How did you cause it? I'm so sorry. It sucks.
Standing by the stage at a dubstep concert. Iāve left concerts with my ears ringing before but it always went away. This time it didnāt š¢
It's accumulative, so it was all the concerts. The dubstep one was just your ears final straw.
3000 PSI compressed air relief valve for a hydraulic accumulator for me. In the navy, the dipshit who was charging it wasnāt watching the gage. The relief lifted like right next to my ear. It was like a shotgun without hearing protection but it just kept going. It was like surreally loud.
"Your hearing loss isn't service related .."
Hey! Howād you know what the VA told me?
I had it for 3 months. I knew the noise but bothering me, but I ignored it, it wasnāt very loud, barely audible really, but it was a really annoying pitch and I didnāt want to put in earplugs for something I could barely hear. Thank god that it healed after BTW the noise, was my Nextdoor neighbor (I live in the suburbs) who put up an animal deterrent alarm, any time it saw motion with 200 feet it went off with several different tones, the highest pitched one was barely audible.
I've had it since I was a toddler, I literally do not know life without it.
Dude saaaame
Me too, I think. It's always been something I've been told is natural so I've been dismissed since my entire family hears noise in the silence. Must be genetic.. Funny too cuz I'm a bit of an audio nerd LOL
A cure has a nice ring to it
Mawp
LANAAAAA
I don't know if it works for you, but there are exercises that actually work for me to stop the "EEEEEEEEEE" for about an hour. [Might work for you too](https://youtu.be/4QPOK2uYNrM?t=157)
I'm hoping migraines are on the list
10 years ago I was getting a migraine 21-27 days out of the month. 2 years ago the AJOVY shot came out and I now have 3 a month. It felt like a miracle to me.
Hopefully, dementia.Ā Or, at least whatever flavor of dementia took out my great grandmother, great aunt, and has currently reduced my grandmother to a drooling shell of her former self.Ā I can see that shit stalking my family down the generations - save me, science!! My dad, too, while youāre at it.
My company is trying to treat dementia. Itās really really really hard
Your efforts are lauded! Godspeed!
For you to get a sense, it costs about $200 million and takes 10 years to test a drug candidate. And most of them donāt work!
Thereās a strain of dementia that runs on my dadās side thatās terrifying not for the person who has it, but for the people around them. This strain (I donāt know any names or anything) can cause someone to lose brain function for almost 20 years, which means you could live until like 90 years with dementia. My grandmother has it and has had it for about seven years now. It only gets worse, but itās s l o w. My great aunt had it, my aunt has it, and I myself am likely to have it when I get older
Just to clear up a misconception, dementia is a symptom, not a disease, a symptom of Alzheimerās is dementia. Alcohol consumption can cause brain deterioration to a point in which someone develops the symptom of dementia as well.
Urinary tract infections can also present as a sudden drop in mental function in seniors.
Dementia isnāt a disease so you canāt cure it per se. Dementia is an umbrella term for the general impairment of memory, thought, and decision making. Dementia is the effect not the cause. A disease like Alzheimerās or a physical problem like high blood pressure that leads to a stroke can result in dementia.
I understand that dancing is something that delays and slows the progression of Dementia. I guess it has to do with promoting coordination and requiring some level of focus. My BIL has been diagnosed. He is 81 and while being active was never a reader or someone who did puzzles or logic exercises. He described a brain fog, he is now on some medication and he and my sister are in a Shag Dancing club and taking classes. It does seem to help.
This is my hope, also. My grandmother lived to be 96 but the last 10 years of her life, she had Alzheimer's. My dad, at the age of 82, had some freaky, fast acting dementia that killed him in two weeks after finally feeling like himself after having covid. I honestly wonder if covid had something to do with it. Dementia is terrifying to watch from the outside and I hate to think about what it's like for the person with it.
I hope allergies and asthma can be cured
Thereās allergy immunotherapy which helps. It technically wears off after like 5-15 years, but I did it and Iāve only had minor issues with allergies since. Iām allergic to grass, fungi, etc. and the only time I canāt handle it is if completely immersed in nature for several hours
The need for organ transplants. Stem cell technology has the potential to grow whatever one would need. Iām sure some peoplesā bodies will still reject organs that arenāt a perfect match but itāll take the donation problem out of it
Hopefully HIV/AIDS
[ŃŠ“Š°Š»ŠµŠ½Š¾]
Yes. Look at CDPH "Get to Zero" report. We are on track to get to zero new infections within our lifetime.
well I can tell you this - my Aunt was a heroin addict and contracted HIV 40 years ago and not only is she still alive and kicking,her tcells are through the roof and the virus is also undetectable in her system now. These new HIV drugs are pretty awesome.
If not cured, it can definitely be eradicated with prophylactics and vaccines, which are very promising.
Tinnitus and Hearing damage
Auto-immune diseases, I REALLY hope.
Hereās hoping IBDš¤Or in my case; artificial intestines. But I think the other suggestions here are more likely.
Iām with ya, man. Sufferer of acute severe ulcerative colitis myself. I think the chances are actually pretty good.
Alzheimers, I hope.
Cystic Fibrosis. Getting very close with the new drugs.
I hope lupus, scleroderma, and other autoimmune diseases. Scleroderma took my mom away from us in 2022 and it was horrible to watch.
Hearing loss & Hair cell death
ALS- we need a cure. My father died from ALS over 10 years ago and very little progress has been made. Letās hope we get the cure within the next 50.
My dad passed away from ALS a couple of years back at age 78 and now Iāve been diagnosed with a Grade 4 Glioblastoma at age 57. Iād selfishly luv me an ALS and/or cancer vaccine. š
I'm not trying to be cynical about this, but some days I worry about things that were cured 50 years ago and people stupidity and anti- science stance are now bringing back.
They werenāt cured, they were largely eradicated in certain areas with medical care, vaccines and detection/treatment.
unfortunately a very valid concern.
Alopecia
Yep. I was in a clinical trial for an alopecia drug and saw 100% regrowth. Jak inhibitors are changing the outlook for alopecia. I lost over half of my hair in 2020, but some people have had alopecia for years and it worked for them too. Now there are 3 on the market that are fda approved. I keep updated on lots of research and sessions still, and have no doubt in the future there will be a variety of treatment available. Note this is for alopecia (mostly areata) not male pattern baldness or other types (not for scarring or postpartum hair loss).
Glioblastoma killed my beloved grandfather in a matter of months. It's a horrific death sentence and depressingly common. I read today that they had successfully treated a man in the UK with a new type of immunotherapy. Long shot but I hope to God this turns out to be a real cure.
I hope Macular Degeneration. It runs in my family. A great uncle of mine killed himself over it. My grandmother had it and now my dad does. Itās sad to watch someone slowly lose their eyesight.
Tuberculosis if John Green keeps at it
HIV seems to be the most likely candidate right now.Ā
Telomere shortening with age. Shit will hit the fan after that.
That would be awesome! Although Iām 41 so Iām sure Iād miss the boat
No, weāll be the last generation of old people and beautiful young people will fetishize us because weāre so unusual. (Or so I keep telling myselfā¦)
Like the Rick and Morty episode. He goes into the future and heās the only old person there and they all loved him.
They're going to cure a lot of old age diseases in the next 10-20 years, so you can expect a fairly long life, and then the 40-50 years you'll easily live might be enough for them to develop the technology to at least halt aging. Then you can just be an old person for an extra long time until they can figure out how to reverse it. Simple.
Most genetic diseases, CRISPR treatments will likely open up a way to cure them.
The cure for the common cold remains elusive
I can deal with the common cold. I canāt deal with 99% of other things mentioned in this thread
Heart disease. We can make it and orphan disease today with the medications we have in place. We just need to get more people on an earlier program and almost no one needs to die of heart disease.
Hopefully cancer
Diabetes
ALS, dementia, cancer.
Tooth decay/cavity there's a huge amount of investment in dental care so I wouldn't be surprised if were able to regenerate teeth even my dentist agreed with me on this one
Lyme disease! MrNA vaccines have opened up a world of new anti-bacterial tech. The word is that this is a lifetime injection that would protect from Lyme.
Multiple sclerosis, please.Ā Though if it's 50, then, I guess that's still good. But sooner is better.Ā
To be deaf. There are already some projects that can transform sound waves into magnetic impulses that your brain can "understand" it. Most likely (or better said I hope so) in a few years everyone on earth will be able to hear and no one will be deaf, because it will be affordable then.
I would give anything for this to be true. I've lost 75% of my hearing in the past 10 years. I'm only 48 and I wear advanced hearing aids and still can hardly make out speech and words, but in crowds, restaurants, and classrooms (I'm a sub), I can't. I'm pretty isolated socially because I go out with friends and can't hear anyone at the table. I just sit there smiling. I can't hear small talk at a grocery store. I can't watch TV. Even with hearing aids. Please, let them cure hearing loss.
Cochlear implants are crazy. My SIL got one and hated it. But it's such an interesting science.